{"title":"在新兴技术时代应对外周动脉疾病的挑战","authors":"","doi":"10.1016/j.jvsvi.2024.100095","DOIUrl":null,"url":null,"abstract":"<div><p>Peripheral artery disease (PAD) is a significant worldwide health burden, yet it remains woefully underdiagnosed and undertreated. By the time PAD manifests symptomatically, patients may already suffer from critical limb ischemia and require invasive surgical intervention. This can be attributed in part to the heterogeneity of PAD pathogenesis as well as shortcomings in current clinical assessment techniques and standards of care. To address these challenges, clinicians need new approaches to prevent, identify, and treat patients at risk for PAD. In this article, we present three clinical cases that exemplify different needs faced by patients with PAD and their providers. These include the need for improved methods of disease detection, more efficient long-term care, and less invasive treatment strategies. The case studies drive our subsequent review and discussion of key areas of translational research that may address each of these needs. The primary objective of this review is to evaluate the current limitations of clinical practice and survey the landscape of emerging research that will hopefully allow clinicians in the near future to better identify and treat patients with PAD. This research encompasses both technological advances in the diagnosis and treatment of the disease, as well as the development of new strategies for optimizing patient management and care delivery. When combined, these different areas of research will address some of the most pressing challenges posed by PAD and will help usher in a new era of holistic, patient-centric care.</p></div>","PeriodicalId":74034,"journal":{"name":"JVS-vascular insights","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949912724000436/pdfft?md5=636708aed3fbbc2fa3705b1d91ddca28&pid=1-s2.0-S2949912724000436-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Facing the challenges of peripheral arterial disease in the era of emerging technologies\",\"authors\":\"\",\"doi\":\"10.1016/j.jvsvi.2024.100095\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Peripheral artery disease (PAD) is a significant worldwide health burden, yet it remains woefully underdiagnosed and undertreated. By the time PAD manifests symptomatically, patients may already suffer from critical limb ischemia and require invasive surgical intervention. This can be attributed in part to the heterogeneity of PAD pathogenesis as well as shortcomings in current clinical assessment techniques and standards of care. To address these challenges, clinicians need new approaches to prevent, identify, and treat patients at risk for PAD. In this article, we present three clinical cases that exemplify different needs faced by patients with PAD and their providers. These include the need for improved methods of disease detection, more efficient long-term care, and less invasive treatment strategies. The case studies drive our subsequent review and discussion of key areas of translational research that may address each of these needs. The primary objective of this review is to evaluate the current limitations of clinical practice and survey the landscape of emerging research that will hopefully allow clinicians in the near future to better identify and treat patients with PAD. This research encompasses both technological advances in the diagnosis and treatment of the disease, as well as the development of new strategies for optimizing patient management and care delivery. 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引用次数: 0
摘要
外周动脉疾病(PAD)是世界性的重大健康负担,但其诊断和治疗仍然严重不足。当 PAD 出现症状时,患者可能已经出现严重的肢体缺血,需要进行侵入性手术干预。这部分归因于 PAD 发病机制的异质性以及当前临床评估技术和护理标准的缺陷。为了应对这些挑战,临床医生需要新的方法来预防、识别和治疗有 PAD 风险的患者。在本文中,我们介绍了三个临床病例,这些病例体现了 PAD 患者及其医疗服务提供者所面临的不同需求。这些需求包括需要改进疾病检测方法、更有效的长期护理以及创伤性更小的治疗策略。在这些病例研究的推动下,我们随后回顾并讨论了可满足上述需求的转化研究的关键领域。本综述的主要目的是评估当前临床实践的局限性,并对新兴研究的前景进行调查,希望在不久的将来能让临床医生更好地识别和治疗 PAD 患者。这些研究既包括疾病诊断和治疗方面的技术进步,也包括优化患者管理和护理服务的新策略的开发。这些不同领域的研究结合在一起,将能解决 PAD 带来的一些最紧迫的挑战,并有助于开创一个以患者为中心的全面护理新时代。
Facing the challenges of peripheral arterial disease in the era of emerging technologies
Peripheral artery disease (PAD) is a significant worldwide health burden, yet it remains woefully underdiagnosed and undertreated. By the time PAD manifests symptomatically, patients may already suffer from critical limb ischemia and require invasive surgical intervention. This can be attributed in part to the heterogeneity of PAD pathogenesis as well as shortcomings in current clinical assessment techniques and standards of care. To address these challenges, clinicians need new approaches to prevent, identify, and treat patients at risk for PAD. In this article, we present three clinical cases that exemplify different needs faced by patients with PAD and their providers. These include the need for improved methods of disease detection, more efficient long-term care, and less invasive treatment strategies. The case studies drive our subsequent review and discussion of key areas of translational research that may address each of these needs. The primary objective of this review is to evaluate the current limitations of clinical practice and survey the landscape of emerging research that will hopefully allow clinicians in the near future to better identify and treat patients with PAD. This research encompasses both technological advances in the diagnosis and treatment of the disease, as well as the development of new strategies for optimizing patient management and care delivery. When combined, these different areas of research will address some of the most pressing challenges posed by PAD and will help usher in a new era of holistic, patient-centric care.