血管内腹部动脉瘤修复术后髂肢闭塞的预测因素:根据主动脉髂解剖、血管内手术和动脉瘤重塑确定

IF 2.8 3区 医学 Q1 Pharmacology, Toxicology and Pharmaceutics
Zihui Yuan, Chao Du, Yun You, Jian Wang
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Fourteen patients presented with ILO and were compared with 52 control patients with patent endograft limb over at least 1-year of follow-up. The tortuosity indices of the common iliac artery (CIA) and endograft iliac limb to vessel oversizing were significantly larger in the ILO group than in the patent endograft limb group. The CIA index of tortuosity ≥1.08, and endograft iliac limb to vessel oversizing ≥18.8% were independent predictors for ILO. During the follow-up of all patients, the proximal aortic neck and CIA diameters increased, aneurysm sac diameter decreased, and aortic neck and aortic length increased. The aortoiliac length increased over time in patients with patent endograft limb but not in patients with ILO. A change in the lowest renal artery-left iliac bifurcation distance ≦0.07 mm increased the risk of ILO. Conclusion ILO is predisposed to occur when the CIA index of tortuosity ≥1.08 and endograft iliac limb to vessel oversizing ≥18.8% are present. 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引用次数: 0

摘要

目的 髂肢闭塞(ILO)是血管内腹部动脉瘤修补术(EVAR)的一种严重并发症。本研究旨在从主动脉髂形态、血管内手术相关参数和动脉瘤重塑特征中确定 ILO 的预测因素。患者和方法 采用单变量分析方法对患者的人口统计学特征、EVAR 前动脉瘤的解剖学特征、血管内手术的详细情况、EVAR 后动脉瘤重塑的结果进行了分析和比较。随后对具有统计学意义的因素进行了 Cox 回归和 Kaplan-Meier 分析。结果 2013年1月至2022年4月期间,66名患者被纳入本研究。14名患者出现了ILO,并与52名内膜移植肢体通畅的对照组患者进行了至少1年的随访比较。ILO组患者的髂总动脉(CIA)迂曲指数和内植物髂肢血管过大指数明显大于内植物髂肢通畅组患者。髂总动脉迂曲指数≥1.08和内膜移植髂肢与血管过长率≥18.8%是预测ILO的独立指标。在所有患者的随访过程中,近端主动脉颈和 CIA 直径增大,动脉瘤囊直径减小,主动脉颈和主动脉长度增加。在内膜移植肢通畅的患者中,主动脉髂骨长度随着时间的推移而增加,而在 ILO 患者中则没有。最低肾动脉-左髂分叉距离的变化≦0.07毫米会增加ILO的风险。结论 当CIA迂曲指数≥1.08和内移植物髂肢与血管过大≥18.8%时,容易发生ILO。EVAR 术后会出现明显的主动脉髂骨重塑,包括近端主动脉颈扩张、颈变直、动脉瘤囊消退、髂动脉扩大和主动脉延长。在内膜移植肢通畅的患者中可以观察到主动脉髂动脉拉长,而在 ILO 患者中则观察不到。ILO 与术后测量值相比,最低肾动脉-左髂分叉的变化≦ 0.07 mm。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Predictive Factors for Iliac Limb Occlusions After Endovascular Abdominal Aneurysm Repair: Determined from Aortoiliac Anatomy, Endovascular Procedures, and Aneurysmal Remodeling
Purpose Iliac limb occlusion (ILO) is a serious complication of endovascular abdominal aneurysm repair (EVAR). This study aimed to identify predictive factors for ILO derived from aortoiliac morphology, endovascular procedure-related parameters, and aneurysmal remodeling characteristics. Patients and Methods Patient demographics, pre-EVAR anatomical characteristics of the aneurysm, endovascular procedure details, and post-EVAR aneurysmal remodeling outcomes were analyzed and compared using univariate analysis. Statistically significant factors were subsequently subjected to Cox regression and Kaplan–Meier analyses. Results Between January 2013 and April 2022, 66 patients were included in this study. Fourteen patients presented with ILO and were compared with 52 control patients with patent endograft limb over at least 1-year of follow-up. The tortuosity indices of the common iliac artery (CIA) and endograft iliac limb to vessel oversizing were significantly larger in the ILO group than in the patent endograft limb group. The CIA index of tortuosity ≥1.08, and endograft iliac limb to vessel oversizing ≥18.8% were independent predictors for ILO. During the follow-up of all patients, the proximal aortic neck and CIA diameters increased, aneurysm sac diameter decreased, and aortic neck and aortic length increased. The aortoiliac length increased over time in patients with patent endograft limb but not in patients with ILO. A change in the lowest renal artery-left iliac bifurcation distance ≦0.07 mm increased the risk of ILO. Conclusion ILO is predisposed to occur when the CIA index of tortuosity ≥1.08 and endograft iliac limb to vessel oversizing ≥18.8% are present. Significant aortoiliac remodeling, including proximal aortic neck dilatation, neck straightening, aneurysmal sac regression, iliac artery enlargement, and aortic lengthening, occurs after EVAR. Aortoiliac elongation was observed in patients with patent endograft limb, but not in patients with ILO. ILO was associated with a change in the lowest renal artery–left iliac bifurcation from the postoperative measurements ≦ 0.07 mm.
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来源期刊
Therapeutics and Clinical Risk Management
Therapeutics and Clinical Risk Management HEALTH CARE SCIENCES & SERVICES-
CiteScore
5.30
自引率
3.60%
发文量
139
审稿时长
16 weeks
期刊介绍: Therapeutics and Clinical Risk Management is an international, peer-reviewed journal of clinical therapeutics and risk management, focusing on concise rapid reporting of clinical studies in all therapeutic areas, outcomes, safety, and programs for the effective, safe, and sustained use of medicines, therapeutic and surgical interventions in all clinical areas. The journal welcomes submissions covering original research, clinical and epidemiological studies, reviews, guidelines, expert opinion and commentary. The journal will consider case reports but only if they make a valuable and original contribution to the literature. As of 18th March 2019, Therapeutics and Clinical Risk Management will no longer consider meta-analyses for publication. The journal does not accept study protocols, animal-based or cell line-based studies.
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