MORPHOLOGICAL FEATURES OF BIOPSY SAMPLES OF THE ORAL MUCOSA IN PATIENTS WITH VIRAL HEPATITIS B AND C

Abstract Background: Currently, diseases of the oral mucosa and periodontal disease are an important problem in dentistry. Studies of the oral cavity in chronic diffuse liver diseases are of great interest to clinicians since pathological processes developing in the liver, as a rule, lead to organic and functional disorders in the oral mucosa. Purpose: The aim of the study was to reveal the morphological features of biopsy samples of the oral mucosa in patients with HBV and HCV. Materials and methods: The study involved 95 patients with HBV, 96 patients with HCV with lesions of the oral cavity and periodontium, as well as 100 patients in the control group without HBV and without HCV, but with lesions of the oral cavity and periodontium. The age of the patients ranged from 21-64 years. In all the groups we examined, 20 morphological studies were carried out. Results: To study the dental status, patients' complaints and data from a clinical examination of the oral cavity were taken into account, which included: external examination of the lips and corners of the mouth, assessment of the condition of various parts of the oral mucosa. To confirm the results of clinical data, we conducted a morphological study of a biopsy sample of the oral mucosa. Biopsies were taken from the affected areas of the oral mucosa. Conclusion: During a pathomorphological study of OM in viral hepatitis B and C, inflammatory infiltration, circulatory disorders and dystrophic changes in the squamous epithelium were detected in all patients, fibrosis - in all patients with HCV. Lymphoplasmacytic infiltration was detected in almost all patients with HBV and HCV