基因信息的价值和需求与模糊厌恶再探讨

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-05-22 DOI:10.1111/rmir.12277

Stefan Felder, Dilek Sevim

{"title":"基因信息的价值和需求与模糊厌恶再探讨","authors":"Stefan Felder, Dilek Sevim","doi":"10.1111/rmir.12277","DOIUrl":null,"url":null,"abstract":"We use the smooth ambiguity model to show that ambiguity aversion increases the value of and demand for genetic information for low prior beliefs of carrying a genetic mutation. We also examine an extension based on the ex ante uncertainty of the test results. The extended model, which accommodates ambiguity aversion only in the presence of new information, lowers the value of genetic information and leads to information avoidance. If this behavior is sufficiently strong, it could explain the low demand observed for genetic tests.","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":"62 52","pages":""},"PeriodicalIF":16.4000,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Value and demand for genetic information and ambiguity aversion revisited\",\"authors\":\"Stefan Felder, Dilek Sevim\",\"doi\":\"10.1111/rmir.12277\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"We use the smooth ambiguity model to show that ambiguity aversion increases the value of and demand for genetic information for low prior beliefs of carrying a genetic mutation. We also examine an extension based on the ex ante uncertainty of the test results. The extended model, which accommodates ambiguity aversion only in the presence of new information, lowers the value of genetic information and leads to information avoidance. If this behavior is sufficiently strong, it could explain the low demand observed for genetic tests.\",\"PeriodicalId\":1,\"journal\":{\"name\":\"Accounts of Chemical Research\",\"volume\":\"62 52\",\"pages\":\"\"},\"PeriodicalIF\":16.4000,\"publicationDate\":\"2024-05-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Accounts of Chemical Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1111/rmir.12277\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1111/rmir.12277","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}

引用次数: 0

摘要

我们使用平滑模糊模型来说明，在携带基因突变的先验信念较低的情况下，模糊厌恶会增加基因信息的价值和需求。我们还研究了基于检测结果事先不确定性的扩展模型。扩展模型只在出现新信息时才考虑模糊厌恶，它降低了遗传信息的价值，并导致信息回避。如果这种行为足够强烈，它就可以解释对基因检测的低需求。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Value and demand for genetic information and ambiguity aversion revisited

We use the smooth ambiguity model to show that ambiguity aversion increases the value of and demand for genetic information for low prior beliefs of carrying a genetic mutation. We also examine an extension based on the ex ante uncertainty of the test results. The extended model, which accommodates ambiguity aversion only in the presence of new information, lowers the value of genetic information and leads to information avoidance. If this behavior is sufficiently strong, it could explain the low demand observed for genetic tests.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.