慢性子宫内膜炎抗生素治疗后的胚胎移植时机

IF 2 4区医学 Q2 OBSTETRICS & GYNECOLOGY

Taiwanese Journal of Obstetrics & Gynecology Pub Date : 2024-05-01 DOI:10.1016/j.tjog.2024.02.005

Xiao-Xiao Hu, Liu Liu, Li-Juan Zhao, Hong-Fei Jiang, Song-Ying Zhang

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引用次数: 0

摘要

材料与方法2021年，一家大型大学附属生殖中心通过回顾性分析共招募了184名患者。部分患者选择在第一轮抗生素治疗的同一月经周期进行胚胎移植（第 1 组，n = 29）。结果第一组患者的生化妊娠率、临床妊娠率和活产率显著低于第二组（P < 0.05）和第三组（P < 0.05）。比较影响因素后，我们发现抗生素治疗后下一周期的胚胎移植临床妊娠率高于第 1 组（OR = 3.2，p < 0.05）和第 3 组（OR = 2.5，p < 0.05）。结论这些研究结果表明，在下一个月经周期进行胚胎移植是最佳时机。在第一轮治疗的同一月经周期进行胚胎移植会降低妊娠率。

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The timing for embryo transfer after antibiotic therapy for chronic endometritis

Objective

To explore the optimal timing of embryo transfer after the first round treatment of chronic endometritis (CE) in vitro.

Materials and methods

A total of 184 patients were recruited from a retrospective analysis of a large university-affiliated reproduction center in 2021. Some people chose to undergo embryo transfer in the same menstrual cycle with the first round of antibiotic treatment (Group 1, n = 29). Others received embryo transfer in the next cycle after the first round of treatment (Group 2, n = 69) or even one cycle later (Group 3，n = 96).

Results

Patients in Group 1 got signiﬁcantly lower biochemical pregnancy rate and clinical pregnancy rate and live birth rate than Group 2 (p < 0.05) and also Group 3 (p < 0.05). Then after comparing the influence factors, we found embryo transfer in the next cycle after antibiotic treatment had a higher clinical pregnancy rate than group 1 (OR = 3.2 p < 0.05) and group 3(OR = 2.5, p < 0.05). The live birth rate in group 2 was higher than group 1(OR = 3.5, p < 0.05).

Conclusion

These findings illustrate that embryo transfer in the next menstrual cycle is the optimal time. Embryo transfer in the same menstrual cycle with the first round of treatment reduces the pregnancy rate.

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来源期刊

Taiwanese Journal of Obstetrics & Gynecology OBSTETRICS & GYNECOLOGY-

CiteScore

3.60

自引率

23.80%

发文量

207

审稿时长

4-8 weeks

期刊介绍： Taiwanese Journal of Obstetrics and Gynecology is a peer-reviewed journal and open access publishing editorials, reviews, original articles, short communications, case reports, research letters, correspondence and letters to the editor in the field of obstetrics and gynecology. The aims of the journal are to: 1.Publish cutting-edge, innovative and topical research that addresses screening, diagnosis, management and care in women''s health 2.Deliver evidence-based information 3.Promote the sharing of clinical experience 4.Address women-related health promotion The journal provides comprehensive coverage of topics in obstetrics & gynecology and women''s health including maternal-fetal medicine, reproductive endocrinology/infertility, and gynecologic oncology. Taiwan Association of Obstetrics and Gynecology.