资源匮乏地区糖尿病管理中心的用药错误。

Pub Date : 2024-01-01 DOI:10.3233/JRS-230062
Frank Yaw Obeng, Seth Kwabena Amponsah, Emmanuel Kwaku Ofori, Daniel Kwame Afriyie
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引用次数: 0

摘要

背景:众所周知,用药错误会导致药物不良反应、入院和死亡。在大多数资源匮乏的环境中,用药错误时有发生,但却没有记录:本研究旨在调查加纳 Komfo Anokye 教学医院(KATH)糖尿病诊所的用药错误:研究结合了定性和定量数据收集方法。定量方面包括回顾性审查两年内(2019 年 1 月 1 日至 2021 年 12 月 31 日)的患者文件夹。对患者文件夹的审查旨在确定可能存在的用药错误。定性部分通过对医护人员的访谈,探讨了与用药错误相关的潜在因素和经验。采用访谈指南对 KATH 的 10 名医护人员进行了访谈:结果:共检索到 264 份患者文件夹。大部分患者(23.11%)年龄在 18 至 25 岁之间,女性(52.27%)多于男性。约 60% 的患者合并有糖尿病和高血压。用药错误的总体发生率为 18.18%。最常见的用药错误类型是药物配方错误(19 人,占 39.58%)。约 47.92% 的用药错误导致了不良事件,而这主要是由抗糖尿病药物(47.83%)和抗高血压药物(34.78%)引起的。年龄在 26-35 岁的患者[aOR:0.31,CI:0.11-0.90]发生用药错误的几率较低,而合并糖尿病和高血压的患者[aOR:5.95,CI:2.43-14.60]发生用药错误的几率较高。患者人数多、工作人员数量少、医护人员对药物了解不足是导致用药错误的因素:结论:该糖尿病诊所的用药失误率中等偏高,而且这些失误导致了一系列不良事件。年龄、糖尿病和高血压合并症、患者人数多、医护人员数量少以及药物知识不足被认为是影响用药错误的因素。
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Medication errors at a diabetes management center in a resource-poor setting.

Background: Medication errors are known to cause adverse drug reactions, hospital admissions and mortality. In most resource-poor settings, medication errors occur but are undocumented.

Objective: This study sought to investigate medication errors in a diabetic clinic at Komfo Anokye Teaching Hospital (KATH), Ghana.

Methods: The research combined both qualitative and quantitative data collection methods. The quantitative aspect involved retrospectively reviewing patient folders over two years (1st January 2019 to 31st December 2021). Patients' folders were reviewed to identify possible medication errors. The qualitative arm explored underlying factors and experiences related to medication errors through interviews with healthcare workers. Ten healthcare professionals at KATH were interviewed using an interview guide.

Results: A total of 264 patients' folders were retrieved. The majority (23.11%) of the patients were between 18 and 25 y.o., and there were more females (52.27%) than males. About 60% of the patients had diabetes and hypertension comorbidity. The overall prevalence of medication errors was 18.18%. The most prevalent type of medication error identified was wrong drug formulation (n = 19, 39.58%). About 47.92% of the medication errors resulted in adverse events and this was predominantly caused by antidiabetic drugs (47.83%) and anti-hypertensive drugs (34.78%). Patients in the age category of 26-35 y.o. [aOR: 0.31, CI: 0.11-0.90] had reduced odds of medication errors whilst patients with comorbidity of diabetes and hypertension [aOR: 5.95, CI: 2.43-14.60] had an increased odds of medication errors. Large patient population, low staff numbers and inadequate knowledge of drugs by healthcare workers were factors that contributed to medication errors.

Conclusion: Medication errors was moderately high in this diabetic clinic, and the errors led to a number of adverse events. Age, diabetes and hypertension comorbidity, large patient population, low staff numbers, and inadequate knowledge about drugs were identified as factors that influenced medication errors.

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