非老年急性肾损伤:临床特征和死亡率。

IF 1.3 Q3 UROLOGY & NEPHROLOGY
Rafael Peixoto Lima Dias, Daniella Bezerra Duarte, Danilo de Castro Bulhões Mascarenhas Barbosa, Rodrigo Peixoto Campos
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引用次数: 0

摘要

导言:非老年患者在住院患者中所占比例不断上升,急性肾损伤(AKI)在这一人群中很常见。因此,分析这一人群的临床特征及其对死亡率的影响非常重要:方法:对一家三甲医院 2013 年至 2022 年间的非高龄急性肾损伤患者进行回顾性研究。仅考虑最近一次入院的患者,排除数据不完整的患者。通过逻辑回归分析确定死亡风险因素。P值小于0.05为具有统计学意义:共纳入 150 名患者,中位年龄为 93.0 岁(91.2-95.0),男性占样本的 42.7%。败血症是导致急性肾损伤的最常见原因(53.3%),其次是脱水/低血容量(17.7%)和心力衰竭(17.7%)。39.3%的患者住进了重症监护室,14.7%的患者接受了机械通气,22.7%的患者使用了血管加压药,6.7%的患者接受了肾脏替代治疗(RRT)。56.7%的患者死亡。作为 AKI 病因的脱水/低血容量与较低的死亡风险相关(OR 0.18; 95% CI 0.04-0.77, p = 0.020)。KDIGO3期(OR 3.15;95% CI 1.17-8.47,p = 0.023)、入住ICU(OR 12.27;95% CI 3.03-49.74,p <0.001)和少尿(OR 5.77;95% CI 1.98-16.85,p = 0.001)与死亡率相关:结论:患有 AKI 的非老年患者死亡率很高,AKI KDIGO 3 期、少尿和入住 ICU 与死亡有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Acute kidney injury in nonagenarians: clinical characteristics and mortality.

Introduction: Nonagenarians constitute a rising percentage of inpatients, with acute kidney injury (AKI) being frequent in this population. Thus, it is important to analyze the clinical characteristics of this demographic and their impact on mortality.

Methods: Retrospective study of nonagenarian patients with AKI at a tertiary hospital between 2013 and 2022. Only the latest hospital admission was considered, and patients with incomplete data were excluded. A logistic regression analysis was conducted to define risk factors for mortality. A p-value < 0.05 was considered statistically significant.

Results: A total of 150 patients were included, with a median age of 93.0 years (91.2-95.0), and males accounting for 42.7% of the sample. Sepsis was the most common cause of AKI (53.3%), followed by dehydration/hypovolemia (17.7%), and heart failure (17.7%). ICU admission occurred in 39.3% of patients, mechanical ventilation in 14.7%, vasopressors use in 22.7% and renal replacement therapy (RRT) in 6.7%. Death occurred in 56.7% of patients. Dehydration/hypovolemia as an etiology of AKI was associated with a lower risk of mortality (OR 0.18; 95% CI 0.04-0.77, p = 0.020). KDIGO stage 3 (OR 3.15; 95% CI 1.17-8.47, p = 0.023), ICU admission (OR 12.27; 95% CI 3.03-49.74, p < 0.001), and oliguria (OR 5.77; 95% CI 1.98-16.85, p = 0.001) were associated with mortality.

Conclusion: AKI nonagenarians had a high mortality rate, with AKI KDIGO stage 3, oliguria, and ICU admission being associated with death.

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来源期刊
CiteScore
2.20
自引率
16.70%
发文量
208
审稿时长
16 weeks
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