膀胱内注射卡介苗（BCG）后脑深部刺激系统感染牛分枝杆菌。

IF 4 3区医学 Q2 NEUROSCIENCES

Journal of Parkinson's disease Pub Date : 2024-01-01 DOI:10.3233/JPD-230426

Linda E Spruijt, Arne Mosch, Carel F E Hoffmann, Cees van Nieuwkoop, Jasper D Tijsterman, Rodi Zutt, Niels A van der Gaag, M Fiorella Contarino

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引用次数: 0

摘要

脑深部刺激（DBS）是治疗帕金森病的一种先进疗法。我们描述了一名 71 岁的患者，在作为膀胱癌辅助治疗手段进行卡介苗膀胱内注射后不久，DBS 感染了牛分枝杆菌。患者在接受利福平、异烟肼和乙胺丁醇治疗 3 个月后获得成功。该病例表明，医生需要意识到这种感染的风险，并在常规培养的基础上增加特异性分枝杆菌检测。

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Mycobacterium bovis Infection of a Deep Brain Stimulation System Following Intravesical Bacillus Calmette-Guérin (BCG) Instillation.

Deep brain stimulation (DBS) is an advanced treatment in Parkinson's disease. We describe a 71-year-old patient in whom the DBS got infected with Mycobacterium bovis shortly after intravesical BCG instillations as an adjuvant treatment of bladder cancer. The DBS internal pulse generator and extension wires had to be replaced, and the patient was treated successfully with rifampicin, isoniazid, and ethambutol during three months. This case suggests that physicians need to be aware of the risk of this kind of infection and add a specific Mycobacterial test to the regular cultures.

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来源期刊

Journal of Parkinson's disease NEUROSCIENCES-

CiteScore

8.40

自引率

5.80%

发文量

338

审稿时长

>12 weeks

期刊介绍： The Journal of Parkinson''s Disease (JPD) publishes original research in basic science, translational research and clinical medicine in Parkinson’s disease in cooperation with the Journal of Alzheimer''s Disease. It features a first class Editorial Board and provides rigorous peer review and rapid online publication.