用于无创检测心房和心室间不同步的码分多点射频近场心脏传感系统

IF 3 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC
Zhewei Ye;Chenming Li;Yankai Mao;Juhong Zhang;Wenbin Zhang;Yulin Zhou;Qijun Hu;Shilie Zheng;Xiaonan Hui;Xianmin Zhang
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引用次数: 0

摘要

监测患者的心脏机械不同步在心血管疾病和心脏再同步化治疗(CRT)中具有举足轻重的作用,但目前的方法对操作人员的技能和经验要求很高。此外,临床仪器还受到高标准操作条件、硬件和维护成本的限制,导致其在日常生活监测中的应用受到限制。为了解决这些问题,我们提出了一种码分多点近场心脏射频传感系统,该系统可将心腔的机械运动直接调制为射频信号,通过处理和分析得到的信号不仅可以定位心电图(ECG)中的 P 波、QRS 波和 T 波,还可用于分析房室机械不同步和室间隔机械不同步。此外,为了减少不同信道信号之间的串扰,提高数字信号的动态范围,多传感点接入采用了码分技术。射频传感系统可随时设计为高采样率(在本研究中为 50 kSps),以恢复心脏的高频机械动态。本研究中展示的系统可对心腔进行 4 通道心脏监测,具有高动态范围、20 微秒的时间分辨率和 25 千赫的频率响应。这种监测心跳机械运动的新方法为进一步探索心血管疾病和 CRT 治疗提供了新的候选方案。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Code Division Multi-Point RF Near-Field Cardiac Sensing System for Noninvasive Atrioventricular and Interventricular Dyssynchrony Detection
Monitoring cardiac mechanical dyssynchrony of a patient has a pivotal role in the cardiovascular disease and cardiac resynchronization therapy (CRT), however current approaches highly demand on the operator's skill and experience. In addition, the clinical instrument is limited by high standard operation conditions and hardware and maintenance costs, which leads to restricted deployment in daily life monitoring. To solve the problems, we propose a code division multi-point near-field cardiac RF sensing system that the mechanical movements of the heart chambers can be directly modulated to the radio frequency signal, from which the signals obtained through processing and analysis can not only locate the P-wave, QRS-waves, and T-wave in the electrocardiogram (ECG), but also they are used to analyze atrioventricular mechanical dyssynchrony and interventricular mechanical dyssynchrony. Furthermore, to reduce the crosstalk between signals from different channels and improve digital signal dynamic range, code division is applied for the multiple sensing points access. The RF sensing system can be readily designed with a high sampling rate, 50 kSps in this work, to recover the high frequency mechanical dynamics of the heart. The system demonstrated in this work provides 4-channel cardiac monitoring on the heart chambers with a high dynamic range, temporal resolution of 20 µs, and frequency response of 25 kHz. This novel method of monitoring the mechanical movement of the heartbeat provides a new candidate to further explore the cardiovascular disease and CRT treatment.
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来源期刊
CiteScore
5.80
自引率
9.40%
发文量
58
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