针对 Megasphaera 物种促进宫颈阴道健康。

IF 14 1区生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Trends in Microbiology Pub Date : 2024-07-01 Epub Date: 2024-05-21 DOI:10.1016/j.tim.2024.04.015

Mariano A Molina, Sneha Biswas, Virginia Núñez-Samudio, Iván Landires

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引用次数: 0

摘要

保持健康的宫颈阴道微生物组（CVM）对女性的健康至关重要；它主要取决于乳酸杆菌的优势。由 Megasphaera 驱动的微生物组失衡会导致感染和疾病。对 Megasphaera 生物学和干预措施的全面研究对于个性化的妇女保健至关重要，需要做出更多努力来减轻宫颈阴道菌群失调带来的风险。

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Targeting Megasphaera species to promote cervicovaginal health.

Maintaining a healthy cervicovaginal microbiome (CVM) is vital for women's wellbeing; it is dependent primarily on Lactobacillus dominance. Microbiome imbalances, driven by Megasphaera species, contribute to infections and disease. Comprehensive research into Megasphaera biology and interventions is crucial for personalized women's healthcare, and additional efforts are required to mitigate the risks posed by cervicovaginal dysbiosis.

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来源期刊

Trends in Microbiology 生物-生化与分子生物学

CiteScore

25.30

自引率

0.60%

发文量

193

审稿时长

6-12 weeks

期刊介绍： Trends in Microbiology serves as a comprehensive, multidisciplinary forum for discussing various aspects of microbiology, spanning cell biology, immunology, genetics, evolution, virology, bacteriology, protozoology, and mycology. In the rapidly evolving field of microbiology, technological advancements, especially in genome sequencing, impact prokaryote biology from pathogens to extremophiles, influencing developments in drugs, vaccines, and industrial enzyme research.