Haruki Akasu, Tomoo Jikuzono, Mami Matsui, Masaomi Sen, Marie Saitou, Osamu Ishibashi, Iwao Sugitani
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引用次数: 0
摘要
背景：探查血流成像（DFI）是一种新的成像技术，它能显示低速血流，而传统的彩色多普勒超声（CDU）很难显示低速血流。在这项研究中，我们比较了 DFI 与 CDU 和甲氧基异丁基异腈（MBI）闪烁扫描在检测原发性甲状旁腺功能亢进（PHPT）患者甲状旁腺腺瘤（PA）方面的作用：2021年3月至2023年3月，87名PHPT患者接受了手术治疗，其中66人患有单发PA。我们为42名患者（5名男性，37名女性；平均年龄：61.6 ± 15.4岁）进行了术前常规超声与CDU、MIBI闪烁扫描和DFI检查：结果：85.7%（36/42）的患者通过 MIBI 闪烁扫描发现了 PA，所有患者均通过 CDU 和 DFI 发现了 PA。CDU 和 DFI 检测到的 PA 血管率分别为 71.4%（30/42）和 85.7%（36/42）。DFI 检测到 6 名在 MIBI 闪烁成像中血管阴性的患者存在血管。此外，在 CDU 检测不到血供的 12 名患者中，有 6 名患者的 DFI 检测到了血供。费雪精确检验显示，DFI确定的高或低血流量与CDU检测到的PA供血血管显著相关（P < 0.001）：结论：DFI有助于术前检测PA血流。
Ultrasonographic Detective Flow Imaging for Evaluating Parathyroid Adenoma in Patients with Primary Hyperparathyroidism.
Background: Detective flow imaging (DFI) is a new imaging technology that displays low-velocity blood flow, which is difficult to visualize on conventional color Doppler ultrasonography (CDU). In this study, we compared the usefulness of DFI with that of CDU and methoxy-isobutyl-isonitrile (MIBI) scintigraphy for detecting parathyroid adenoma (PA) in patients with primary hyperparathyroidism (PHPT).
Methods: From March 2021 to March 2023, 87 PHPT patients underwent surgery, and 66 had a single PA. We performed preoperative conventional ultrasonography with CDU, MIBI scintigraphy, and DFI for 42 patients (5 males and 37 females; mean age: 61.6 ± 15.4 years).
Results: MIBI scintigraphy detected PA in 85.7% (36/42) patients, and both CDU and DFI detected PA in all patients. The rates of vascularity in PA detected by CDU and DFI were 71.4% (30/42) and 85.7% (36/42), respectively. Vascularity was detected by DFI in 6 patients who were negative for vascularity on MIBI scintigraphy. Furthermore, DFI detected blood supply in 6 of the 12 patients with undetectable blood supply on CDU. Fisher's exact test revealed that high or low blood flow, as determined by DFI, was significantly associated with detection of feeding vessels in PA by CDU (P < 0.001).
Conclusions: DFI was useful for preoperative detection of PA blood flow.
期刊介绍：
The international effort to understand, treat and control disease involve clinicians and researchers from many medical and biological science disciplines. The Journal of Nippon Medical School (JNMS) is the official journal of the Medical Association of Nippon Medical School and is dedicated to furthering international exchange of medical science experience and opinion. It provides an international forum for researchers in the fields of bascic and clinical medicine to introduce, discuss and exchange thier novel achievements in biomedical science and a platform for the worldwide dissemination and steering of biomedical knowledge for the benefit of human health and welfare. Properly reasoned discussions disciplined by appropriate references to existing bodies of knowledge or aimed at motivating the creation of such knowledge is the aim of the journal.
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