TiNbZrMo 中等熵生物复合材料的合成与表征:微观结构、机械性能和体外降解。

IF 3.2 4区 医学 Q2 ENGINEERING, BIOMEDICAL
Yakup Say
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引用次数: 0

摘要

本研究报告了以羟基磷灰石(HA)为基础的生物复合材料的合成和表征,其中添加了不同数量(按重量计,1-15 wt.%)的生物中熵合金(BioMEA),用于承重植入应用。由钛、铌、锆和钼组成的生物中熵合金粉末经过 100 小时的机械合金化处理,然后通过粉末冶金技术添加到 HA 中。为了显示 BioMEA 的效果,对其进行了微观结构、密度和机械测试,并通过扫描电子显微镜(SEM)、X 射线衍射仪(XRD)和傅立叶变换红外光谱(FTIR)分析对合成的 BioMEA 进行了表征。此外,还对生物复合材料进行了体外降解行为和生物活性分析。XRD 分析显示,经过 20 小时的机械合金化处理后,形成了 BioMEA。15 wt.% BioMEA 增强生物复合材料的最高密度值为 2.47 g/cm3。添加 BioMEA 增强材料后,硬度和拉伸强度值显著增加,15 wt.% 增强材料的硬度和拉伸强度值最高。压缩测试表明,生物复合材料的抗压强度和变形能力明显提高,添加 15 重量百分比的 BioMEA 时的抗压强度和变形能力值最高。10 wt.% MEA 增强生物复合材料的韧性最高,达到 7.68 kJ/m2。所生产的生物复合材料的弹性模量在 3.5-5.5 GPa 之间,可以解决金属植入材料的高弹性模量造成的应力屏蔽问题。15 wt.% MEA 增强生物复合材料的降解最为严重,降解效应导致所有生物复合材料中 Ca 的减少和 Ti-Ni-Zr-Mo 的增加。这些研究结果表明,HA/BioMEA 生物复合材料有望发展成为具有适度机械和生物特性的先进生物材料,用于承重植入物。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Synthesis and characterization of TiNbZrMo medium-entropy bio-composites: Microstructure, mechanical properties, and in vitro degradation

This study reports the synthesis and characterization of hydroxyapatite (HA)-based bio-composites reinforced with varying amounts (by weight, 1–15 wt.%) of bio-medium entropy alloy (BioMEA) for load-bearing implant applications. BioMEA powders consisting of Ti, Nb, Zr, and Mo were mechanically alloyed for 100 h and subsequently added to HA using powder metallurgy techniques. To show the effect of BioMEA, the microstructure, density, and mechanical tests have been conducted and the synthesized BioMEA was characterized by scanning electron microscope (SEM), x-ray diffractometer (XRD), and Fourier-transform infrared spectroscopy (FTIR) analysis. In addition, in vitro degradation behavior and bioactivity analyses of bio-composites have been conducted. XRD analysis revealed the formation of BioMEA after 20 h of mechanical alloying. The highest density value of 2.47 g/cm3 was found in 15 wt.% BioMEA-reinforced bio-composite. The addition of BioMEA reinforcement led to a significant increase in hardness and tensile strength values, with the highest values observed at 15 wt.% reinforcement. Compression tests demonstrated a significant increase in compressive strength and deformation capability of the bio-composites with the highest values observed at 15 wt.% BioMEA addition. The highest toughness of 7.68 kJ/m2 was measured in 10 wt.% MEA-reinforced bio-composites. The produced bio-composite materials have an elastic modulus between 3.5–5.5 GPa, which may provide a solution to the stress shielding problems caused by the high elastic modulus of metallic implant materials. The most severe degradation occurred in 15 wt.% MEA-reinforced bio-composites, and the effect of degradation caused a decrease in Ca and an increase in Ti-Ni-Zr-Mo in all bio-composites. These findings suggest that HA/BioMEA bio-composites have the potential to be developed as advanced biomaterials with moderate mechanical and biological properties for load-bearing implant applications.

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来源期刊
CiteScore
7.50
自引率
2.90%
发文量
199
审稿时长
12 months
期刊介绍: Journal of Biomedical Materials Research – Part B: Applied Biomaterials is a highly interdisciplinary peer-reviewed journal serving the needs of biomaterials professionals who design, develop, produce and apply biomaterials and medical devices. It has the common focus of biomaterials applied to the human body and covers all disciplines where medical devices are used. Papers are published on biomaterials related to medical device development and manufacture, degradation in the body, nano- and biomimetic- biomaterials interactions, mechanics of biomaterials, implant retrieval and analysis, tissue-biomaterial surface interactions, wound healing, infection, drug delivery, standards and regulation of devices, animal and pre-clinical studies of biomaterials and medical devices, and tissue-biopolymer-material combination products. Manuscripts are published in one of six formats: • original research reports • short research and development reports • scientific reviews • current concepts articles • special reports • editorials Journal of Biomedical Materials Research – Part B: Applied Biomaterials is an official journal of the Society for Biomaterials, Japanese Society for Biomaterials, the Australasian Society for Biomaterials, and the Korean Society for Biomaterials. Manuscripts from all countries are invited but must be in English. Authors are not required to be members of the affiliated Societies, but members of these societies are encouraged to submit their work to the journal for consideration.
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