中国男性酒精依赖症患者体重不足的发生率、社会人口学和临床相关性。

IF 2.1 4区 医学 Q3 SUBSTANCE ABUSE
Huanfen Li, Lifang Zhu, Jie Zhang, Jun Xue
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引用次数: 0

摘要

研究背景体重不足是酒精依赖症患者的一个重要症状,但很少有研究对中国男性患者的体重不足情况进行调查。本研究旨在确定中国男性酒精依赖患者体重不足的发生率、社会人口学和临床相关性:在这项横断面研究中,共招募了 405 名男性酒精依赖住院患者和 383 名健康男性对照者。我们收集了参与者的人口统计学和临床数据,包括人体测量数据。我们首先进行了单变量分析,以确定组间存在显著差异的七个变量:吸烟行为、住院、饮酒、脑梗塞、高血压、汉密尔顿抑郁量表(HAMD)评分和阴性症状评估量表(SANS)评分。然后,采用二元逻辑回归评估它们与体重不足的关系,显著性水平为 0.05:结果:研究对象体重不足的发生率明显高于对照组(2.99% 对 2.87%;P在中国样本中,超过 20% 的男性酒精依赖症患者体重不足。一些人口统计学和临床变量与酒精依赖症患者体重不足有独立相关性。我们需要重点关注有吸烟、脑梗塞、抑郁和更突出的负面症状的酒精依赖症患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prevalence, sociodemographic, and clinical correlates of underweight in a sample of Chinese male alcohol-dependent patients.

Background: Underweight is a significant symptom in alcohol-dependent patients, yet few studies have examined underweight in Chinese male patients. The current study aimed to identify the prevalence, sociodemographic, and clinical correlates of underweight in Chinese male patients with alcohol dependency.

Methods: In this cross-sectional study, 405 male inpatients with alcohol dependence and 383 healthy male controls were recruited. Participants' demographic and clinical data, including anthropometric data, were collected. We first conducted univariate analysis to identify seven variables with significant differences between groups: smoking behavior, hospitalization, alcohol consumption, cerebral infarction, hypertension, Hamilton Depression Scale (HAMD) score, and Scale for Assessment of Negative Symptom (SANS) score. Then, binary logistic regression was used to assess their relationship with underweight, with a significance level of .05.

Results: The prevalence of underweight was significantly higher in the study population than in the control group (2.99% vs. 2.87%; P < .001). Patients with underweight had significantly higher rates of smoking behavior and cerebral infarction, as well as higher scores of SANS and HAMD than non-underweight patients. The non-underweight patients had higher daily alcohol consumption and times of hospitalization. Furthermore, logistic regression analysis showed that smoking behavior [odds ratio (OR) = 2.84, 95% confidence interval (CI) = 1.03-7.80, P = .043)], cerebral infarction (OR = 5.20, 95% CI = 1.13-23.85, P = .036), SANS score (OR = 1.22, 95% CI = 1.16-1.28, P < .001), and HAMD score (OR = 1.06, 95% CI = 1.02-1.11, P = .005) were associated with underweight.

Conclusions: More than 20% of male alcohol-dependent patients in a Chinese sample were underweight. Some demographic and clinical variables independent correlates for underweight in alcohol-dependent patients. We need to focus on alcohol-dependent patients with smoking, cerebral infarction, depression, and more prominent negative symptoms.

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来源期刊
Alcohol and alcoholism
Alcohol and alcoholism 医学-药物滥用
CiteScore
4.70
自引率
3.60%
发文量
62
审稿时长
4-8 weeks
期刊介绍: About the Journal Alcohol and Alcoholism publishes papers on the biomedical, psychological, and sociological aspects of alcoholism and alcohol research, provided that they make a new and significant contribution to knowledge in the field. Papers include new results obtained experimentally, descriptions of new experimental (including clinical) methods of importance to the field of alcohol research and treatment, or new interpretations of existing results. Theoretical contributions are considered equally with papers dealing with experimental work provided that such theoretical contributions are not of a largely speculative or philosophical nature.
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