儿科腹部创伤的预后和严重程度评分的预测价值评估:法国全国队列研究。

IF 4.2 2区 医学 Q1 ANESTHESIOLOGY
European Journal of Anaesthesiology Pub Date : 2024-09-01 Epub Date: 2024-05-20 DOI:10.1097/EJA.0000000000002019
Sidonie Hanna, Juliette Montmayeur, Estelle Vergnaud, Gilles Orliaguet
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引用次数: 0

摘要

背景:小儿闭合性腹部创伤很常见,但其严重程度和对存活率的影响却很难确定。迄今为止,儿科尚无综合腹部受累情况的预后评分:评估儿童闭合性腹部创伤的严重程度、短期和中期预后,以及严重程度评分在预测死亡率方面的表现:设计:回顾性、队列、观察性研究:2015年至2019年期间,在法国儿科一级创伤中心创伤室就诊的0至18岁患者,这些患者有的是单独的闭合性腹部创伤,有的是多发性创伤的一部分:主要结果:主要结果是6个月的死亡率。次要结果为相关并发症和治疗干预,以及所列评分预测死亡率的性能。儿科创伤评分(PTS)、修订创伤评分(RTS)、儿科年龄调整后休克指数(SIPA)评分、反向休克指数乘以格拉斯哥昏迷量表评分(rSIG)、基础缺损、国际正常化比率、格拉斯哥昏迷量表(BIG)、损伤严重程度评分(ISS)、创伤评分和损伤严重程度(TRISS)评分:收集的数据包括入院时的临床、生物学和 CT 扫描数据、最初 24 小时的管理和预后。根据 BIG 评分和 TRISS 方法计算 PTS、RTS、SIPA、rSIG、BIG 和 ISS 评分,并预测死亡率:在 1145 名患者中,149 人符合纳入标准,12 人(8.1%)死亡。在这 12 名死亡患者中,11 人(91.7%)有严重颅脑损伤,11 人(91.7%)输了血制品,7 人接受了氨甲环酸治疗。ROC 曲线分析认为,PTS、RTS、rSIG 和 BIG 评分能准确预测儿科闭合性腹部创伤的死亡率,AUC 至少为 0.92。在阈值为 24.8 时,BIG 评分对死亡率的预测效果最佳[灵敏度为 90%,特异度为 92%,负预测值(NPV)为 99%,曲线下面积(AUC)为 0.93]:PEVALPED是法国第一项评估儿科闭合性腹部创伤预后的研究。PTS、rSIG 和 BIG 评分的使用与急性期相关,BIG 评分的病理生理学意义和准确性使其成为预测儿童闭合性腹部创伤死亡率的有力工具。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prognosis and assessment of the predictive value of severity scores in paediatric abdominal trauma: A French national cohort study.

Background: Paediatric closed abdominal trauma is common, however, its severity and influence on survival are difficult to determine. No prognostic score integrating abdominal involvement exists to date in paediatrics.

Objectives: To evaluate the severity and short-term and medium-term prognosis of closed abdominal trauma in children, and the performance of severity scores in predicting mortality.

Design: Retrospective, cohort, observational study.

Setting and participants: Patients aged 0 to 18 years presenting at the trauma room of a French paediatric Level I Trauma Centre over the period 2015 to 2019 with an isolated closed abdominal trauma or as part of a polytrauma.

Main outcomes: Primary outcome was the six months mortality. Secondary outcomes were related complications and therapeutic interventions, and performance for predicting mortality of the scores listed. Paediatric Trauma Score (PTS), Revised Trauma Score (RTS), Shock Index Paediatric Age-adjusted (SIPA) score, Reverse shock index multiplied by Glasgow Coma Scale score (rSIG), Base Deficit, International Normalised Ratio, and Glasgow Coma Scale (BIG), Injury Severity Score (ISS) and Trauma Score and the Injury Severity (TRISS) score.

Data collection: Data collected include clinical, biological and CT scan data at admission, first 24 h management and prognosis. The PTS, RTS, SIPA, rSIG, BIG and ISS scores were calculated and mortality was predicted according to BIG score and TRISS methodology.

Results: Of 1145 patients, 149 met the inclusion criteria and 12 (8.1%) died. Of the 12 deceased patients, 11 (91.7%) presented with severe head injury, 11 (91.7%) had blood products transfusion and 7 received tranexamic acid. ROC curves analysis concluded that PTS, RTS, rSIG and BIG scores accurately predict mortality in paediatric closed abdominal trauma with AUCs at least 0.92. The BIG score offered the best predictive performance for predicting mortality at a threshold of 24.8 [sensitivity 90%, specificity 92%, negative-predictive value (NPV) 99%, area under the curve (AUC) 0.93].

Conclusion: PEVALPED is the first French study to evaluate the prognosis of paediatric closed abdominal trauma. The use of PTS, rSIG and BIG scores are relevant from the acute phase and the pathophysiological interest and accuracy of the BIG score make it a powerful tool for predicting mortality of closed abdominal trauma in children.

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来源期刊
CiteScore
6.90
自引率
11.10%
发文量
351
审稿时长
6-12 weeks
期刊介绍: The European Journal of Anaesthesiology (EJA) publishes original work of high scientific quality in the field of anaesthesiology, pain, emergency medicine and intensive care. Preference is given to experimental work or clinical observation in man, and to laboratory work of clinical relevance. The journal also publishes commissioned reviews by an authority, editorials, invited commentaries, special articles, pro and con debates, and short reports (correspondences, case reports, short reports of clinical studies).
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