心肌炎和炎症性心肌病的诊断与治疗。证监会心肌炎工作组共识文件

IF 7.2 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS
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引用次数: 0

摘要

心肌炎被定义为心肌炎症,其病因多种多样,包括感染性病原体、药物和自身免疫性疾病。其临床表现也千差万别,除了典型的急性胸痛临床表现外,还包括病因不明的心肌病,其病因可能是炎症。由于某些患者可能会从针对性治疗中获益,因此在首次怀疑患有心肌炎时就应开始寻找病因。该病的诊断和治疗仍存在一些不确定因素。因此,本共识文件旨在为其诊断和治疗提供明确的建议。因此,本文提出了一种诊断算法,明确了何时适合使用心脏磁共振进行无创诊断,何时适合使用心内膜活检进行无创诊断。此外,还讨论了更多新的方面,如何时怀疑潜在的遗传病因。建议涵盖了心肌炎和炎症性心肌病的一般并发症和特定临床实体的管理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Diagnosis and treatment of myocarditis and inflammatory cardiomyopathy. Consensus document of the SEC-Working Group on Myocarditis

Myocarditis is defined as myocardial inflammation and its etiology is highly diverse, including infectious agents, drugs, and autoimmune diseases. The clinical presentation also varies widely, extending beyond the classic clinical picture of acute chest pain, and includes cases of cardiomyopathy of unknown cause whose etiology may be inflammatory. Because certain patients may benefit from targeted treatments, the search for the etiology should begin when myocarditis is first suspected. There remain several areas of uncertainty in the diagnosis and treatment of this disease. Consequently, this consensus document aims to provide clear recommendations for its diagnosis and treatment. Hence, a diagnostic algorithm is proposed, specifying when non-invasive diagnosis with cardiac MR is appropriate vs a noninvasive approach with endomyocardial biopsy. In addition, more novel aspects are discussed, such as when to suspect an underlying genetic etiology. The recommendations cover the management of myocarditis and inflammatory cardiomyopathy, both for general complications and specific clinical entities.

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CiteScore
7.70
自引率
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