{"title":"分散在水合深共晶溶剂中的转移体在角质层中的变形","authors":"Amika Takada, Misato Matsuoka, Mina Sakuragi","doi":"10.1093/chemle/upae074","DOIUrl":null,"url":null,"abstract":"\n The deformation of transfersomes (TFs) dispersed in deep eutectic solvents and applied to the stratum corneum (SC) was evaluated by small-angle X-ray scattering. We found that TFs permeated the SC, while the regularity and period of the multilayer structure of TFs deformed significantly, depending on the SC location and the time after application.","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":"51 1","pages":""},"PeriodicalIF":16.4000,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Deformation of transfersomes dispersed in hydrated deep eutectic solvent in stratum corneum\",\"authors\":\"Amika Takada, Misato Matsuoka, Mina Sakuragi\",\"doi\":\"10.1093/chemle/upae074\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\\n The deformation of transfersomes (TFs) dispersed in deep eutectic solvents and applied to the stratum corneum (SC) was evaluated by small-angle X-ray scattering. We found that TFs permeated the SC, while the regularity and period of the multilayer structure of TFs deformed significantly, depending on the SC location and the time after application.\",\"PeriodicalId\":1,\"journal\":{\"name\":\"Accounts of Chemical Research\",\"volume\":\"51 1\",\"pages\":\"\"},\"PeriodicalIF\":16.4000,\"publicationDate\":\"2024-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Accounts of Chemical Research\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.1093/chemle/upae074\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1093/chemle/upae074","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
摘要
我们通过小角 X 射线散射评估了分散在深共晶溶剂中并涂抹在角质层(SC)上的转移体(TFs)的变形情况。我们发现 TFs 可渗透角质层,而 TFs 多层结构的规则性和周期则随角质层位置和涂抹时间的不同而发生显著变形。
Deformation of transfersomes dispersed in hydrated deep eutectic solvent in stratum corneum
The deformation of transfersomes (TFs) dispersed in deep eutectic solvents and applied to the stratum corneum (SC) was evaluated by small-angle X-ray scattering. We found that TFs permeated the SC, while the regularity and period of the multilayer structure of TFs deformed significantly, depending on the SC location and the time after application.
期刊介绍:
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.