{"title":"分散在水合深共晶溶剂中的转移体在角质层中的变形","authors":"Amika Takada, Misato Matsuoka, Mina Sakuragi","doi":"10.1093/chemle/upae074","DOIUrl":null,"url":null,"abstract":"\n The deformation of transfersomes (TFs) dispersed in deep eutectic solvents and applied to the stratum corneum (SC) was evaluated by small-angle X-ray scattering. We found that TFs permeated the SC, while the regularity and period of the multilayer structure of TFs deformed significantly, depending on the SC location and the time after application.","PeriodicalId":9862,"journal":{"name":"Chemistry Letters","volume":null,"pages":null},"PeriodicalIF":1.4000,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Deformation of transfersomes dispersed in hydrated deep eutectic solvent in stratum corneum\",\"authors\":\"Amika Takada, Misato Matsuoka, Mina Sakuragi\",\"doi\":\"10.1093/chemle/upae074\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\\n The deformation of transfersomes (TFs) dispersed in deep eutectic solvents and applied to the stratum corneum (SC) was evaluated by small-angle X-ray scattering. We found that TFs permeated the SC, while the regularity and period of the multilayer structure of TFs deformed significantly, depending on the SC location and the time after application.\",\"PeriodicalId\":9862,\"journal\":{\"name\":\"Chemistry Letters\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2024-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Chemistry Letters\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.1093/chemle/upae074\",\"RegionNum\":4,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chemistry Letters","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1093/chemle/upae074","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
摘要
我们通过小角 X 射线散射评估了分散在深共晶溶剂中并涂抹在角质层(SC)上的转移体(TFs)的变形情况。我们发现 TFs 可渗透角质层,而 TFs 多层结构的规则性和周期则随角质层位置和涂抹时间的不同而发生显著变形。
Deformation of transfersomes dispersed in hydrated deep eutectic solvent in stratum corneum
The deformation of transfersomes (TFs) dispersed in deep eutectic solvents and applied to the stratum corneum (SC) was evaluated by small-angle X-ray scattering. We found that TFs permeated the SC, while the regularity and period of the multilayer structure of TFs deformed significantly, depending on the SC location and the time after application.