强制表达 LMX1A 可诱导背侧神经命运,并破坏人类胚胎干细胞向腹侧中脑多巴胺能神经元的模式化。

IF 5.9 2区 医学 Q1 CELL & TISSUE ENGINEERING
Pedro Rifes, Janko Kajtez, Josefine Rågård Christiansen, Alrik L. Schörling, Gaurav Singh Rathore, Daniel A Wolf, Andreas Heuer, A. Kirkeby
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引用次数: 0

摘要

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Forced LMX1A expression induces dorsal neural fates and disrupts patterning of human embryonic stem cells into ventral midbrain dopaminergic neurons.
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来源期刊
Stem Cell Reports
Stem Cell Reports CELL & TISSUE ENGINEERING-CELL BIOLOGY
CiteScore
10.50
自引率
1.70%
发文量
200
审稿时长
28 weeks
期刊介绍: Stem Cell Reports publishes high-quality, peer-reviewed research presenting conceptual or practical advances across the breadth of stem cell research and its applications to medicine. Our particular focus on shorter, single-point articles, timely publication, strong editorial decision-making and scientific input by leaders in the field and a "scoop protection" mechanism are reasons to submit your best papers.
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