Continuous flow as an enabling technology for sustainable supramolecular chemistry

Supramolecular chemistry exploits non-covalent intramolecular interactions to form structures such as host-guest complexes and crystalline porous materials. Supramolecular materials have potential for applications in a future sustainable society, such as energy-efficient separation, pollution remediation, or energy storage, but their production frequently relies on unsustainable methods. Flow chemistry is a technique that offers opportunities for ‘greener’ synthesis and that has recently found use in the supramolecular field. This review highlights recent examples to illustrate how flow chemistry can benefit the supramolecular chemist in terms of sustainability, process control, optimisation, and scale, ultimately providing viable routes to applications.