复原力在压力与酒精关系中的作用

IF 4.3 2区 医学 Q1 NEUROSCIENCES
Melanie L. Schwandt , Eva Cullins , Vijay A. Ramchandani
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引用次数: 0

摘要

压力在酒精消费和酒精使用障碍的发病风险中扮演着有据可查的角色。近几十年来,抗压能力的概念--应对并成功适应生活中的压力经历--在成瘾研究领域受到越来越多的关注,已有越来越多的证据表明,抗压能力是防止问题酒精消费、酒精使用障碍风险、障碍严重程度和复发的保护因素。然而,不同的研究在得出这些证据时所使用的概念和方法却大相径庭。有鉴于此,我们撰写了这篇综述,以便更透彻地了解复原力的含义和范围、哪些因素有助于提高复原力、如何衡量复原力以及复原力与酒精相关表型之间的关系。此外,还讨论了通过使用抗逆力建设干预措施进行治疗的意义,以及未来研究抗逆力在酒精使用障碍的病因学和临床结果中的作用的意义。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The role of resilience in the relationship between stress and alcohol

Stress plays a well-documented role in alcohol consumption and the risk for developing alcohol use disorder. The concept of resilience - coping with and successfully adapting to stressful life experiences – has received increasing attention in the field of addiction research in recent decades, and there has been an accumulation of evidence for resilience as a protective factor against problematic alcohol consumption, risk for alcohol use disorder, disorder severity, and relapse. The conceptual and methodological approaches used in the generation of this evidence vary considerably across investigations, however. In light of this, we carried out this review in order to provide a more thorough understanding of the meaning and scope of resilience, what factors contribute to resilience, how it is measured, and how it relates to alcohol-associated phenotypes. Implications for treatment through the use of resilience-building interventions are likewise discussed, as well as implications for future research on the role of resilience in the etiology and clinical outcomes of alcohol use disorder.

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来源期刊
Neurobiology of Stress
Neurobiology of Stress Biochemistry, Genetics and Molecular Biology-Biochemistry
CiteScore
9.40
自引率
4.00%
发文量
74
审稿时长
48 days
期刊介绍: Neurobiology of Stress is a multidisciplinary journal for the publication of original research and review articles on basic, translational and clinical research into stress and related disorders. It will focus on the impact of stress on the brain from cellular to behavioral functions and stress-related neuropsychiatric disorders (such as depression, trauma and anxiety). The translation of basic research findings into real-world applications will be a key aim of the journal. Basic, translational and clinical research on the following topics as they relate to stress will be covered: Molecular substrates and cell signaling, Genetics and epigenetics, Stress circuitry, Structural and physiological plasticity, Developmental Aspects, Laboratory models of stress, Neuroinflammation and pathology, Memory and Cognition, Motivational Processes, Fear and Anxiety, Stress-related neuropsychiatric disorders (including depression, PTSD, substance abuse), Neuropsychopharmacology.
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