Comparison of Autogenous Fresh Demineralized Dentin and Beta-Tricalcium Phosphate in Immediate Implant Placement of Mandibular Molars (Randomized Clinical Controlled Trial)

INTRODUCTION: Autogenous fresh demineralized dentin, a graft used in immediate implant placement, has proven successful. It shares a similar chemical composition to human bone, making it biocompatible and capable of promoting osteoinductive and osteoconductive properties. β-tricalcium phosphate (β-TCP) is a widely employed synthetic bone graft material for filling gaps during immediate implant placement, particularly in posterior molars. OBJECTIVES: To compare the clinical and radiographic effects of fresh demineralized dentin and β-tricalcium phosphate as graft materials on bone density, crestal bone loss, and implant stability used in alveolar bone regeneration for immediate implant placement in mandibular molars. MATERIALS AND METHODS: The study included sixteen patients with unrestorable mandibular molars recruited and randomly allocated into two equal groups. The study group received fresh Demineralized Dentin Grafting (DDG), while the control group received β-tricalcium phosphate. All patients were followed clinically and radiologically for six months to assess parameters such as implant stability, crestal bone loss, and bone density. RESULTS: Crestal bone loss was significantly higher in the β-tricalcium phosphate group compared wtih the DDG group. Implant stability was significantly higher in the DDG group compared with the β-tricalcium phosphate group; the percentage change of bone density was significantly higher in the DDG group compared with the β-Tri Calcium Phosphate group. CONCLUSION: Autogenous fresh demineralized dentin may be a more favorable graft material compared to β-tricalcium phosphate for alveolar bone regeneration in immediate implant placement of mandibular molars. Fresh demineralized dentin was associated with superior crestal