颈动脉内膜剥脱术后原发性闭合与补片闭合的比较：回顾性研究

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-05-08 DOI:10.29333/ejgm/14596

N. Farouk, Ehab M. Abdo, Sameh E Elimam, Waleed E Elshinawy, Abdelaziz A Abdelhafez, Lobna Kh Sakr, W. Abdo, Hayam Abdel-Tawab, Eman A Elhamrawy, Sahar Fares Ahmed, Shymaa Adel Ismael, Mahmoud Kamel Elawady, Samy Ibrahim Kamel, Rehab Elsheikh, Ayman Osama

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引用次数: 0

摘要

目的：本研究旨在提供我们在颈动脉内膜剥脱术（CEA）后进行补片闭合（PAC）和初次闭合（PRC）的经验：本回顾性比较研究包括 106 名接受择期颈动脉内膜剥脱术（CEA）的患者。其中，PRC 组 50 例，PAC 组 56 例。对患者进行围手术期、三个月和一年的随访，以了解手术并发症、中风和再狭窄的情况：结果：术后，两组患者的中风率（6.0% 对 3.6%，P=0.740）、感染率（0.0% 对 3.6%，P=0.520）、血肿率（2.0% 对 3.6%，P=0.520）和再狭窄率（2.0% 对 3.6%，P=0.520）均无明显差异。520）、血肿（2.0% 对 1.8%，P=0.940）、假性动脉瘤（0.0% 对 3.6%，P=0.520）、颅神经损伤（2.0% 对 1.8%，P=0.940）和心脏事件（2.0% 对 1.8%，P=0.940）。三个月后，PRC 组和 PAC 组分别有三名和四名患者失去了随访机会。在三个月的再狭窄率方面，研究组之间没有发现明显差异（2.1% 对 0.0%，P=0.960）。一年后，PRC 组患者的再狭窄率明显更高（14.9% 对 1.9%，P=0.046）。研究中没有患者死亡：结论：CEA联合补片血管成形术可降低再狭窄率。

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Primary versus patch closure after carotid endarterectomy: A retrospective study

Purpose: The present study aimed to provide our experience with patch closure (PAC) and primary closure (PRC) after carotid endarterectomy (CEA). Materials & methods: The present retrospective comparative study included 106 patients submitted to elective CEA. They comprised 50 patients in PRC group and 56 patients in PAC group. Patients were followed perioperatively, at three months and at one year for surgical complications, stroke, and restenosis. Results: Postoperatively, no significant differences were found between the studied groups regarding rates of stroke (6.0% versus 3.6%, p=0.740), infection (0.0% versus 3.6%, p=0.520), hematoma (2.0% versus 1.8%, p=0.940), pseudoaneurysm (0.0% versus 3.6%, p=0.520), cranial nerve injury (2.0% versus 1.8%, p=0.940), and cardiac events (2.0% versus 1.8%, p=0.940). At three months, three patients in PRC group and four in PAC group were lost to follow up. No significant differences were found between the studied groups regarding rate of restenosis at three months (2.1% versus 0.0%, p=0.960). At one year, patients in PRC group experienced significantly higher rate of restenosis (14.9% versus 1.9%, p=0.046). None of the studied patients died. Conclusions: CEA combined with patch angioplasty may be associated with lower restenosis rate.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.