使用去势抗精神病药物的临床注意事项和误区

Q4 Medicine

Ugeskrift for laeger Pub Date : 2024-05-13 DOI:10.61409/v12230776

Niels August Willer Strand, Mette Ødegaard Nielsen, Jimmi Nielsen

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引用次数: 0

摘要

长效注射抗精神病药物（LAI）是一种常用的治疗方式，与口服抗精神病药物相比，它在住院治疗或预防复发方面具有优势。然而，LAI 的药代动力学特性与口服抗精神病药物有很大不同。因此，临床医生有必要增加对LAI的了解，尤其是在开始治疗、改变剂量和中止治疗时。在本综述中，我们总结了 LAI 在临床上的一系列重要特征，并给出了理解 LAI 药代动力学的概念框架。

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Clinical considerations and pitfalls in the use of depot antipsychotics

Long-acting injectable antipsychotics (LAI) is a frequently used treatment modality which has advantages over oral antipsychotics regarding hospitalization or relapse prevention. However, the pharmacokinetic properties of LAI greatly differ from oral antipsychotics. This necessitates an increased knowledge about LAI among clinicians, especially when commencing treatment, changing doses and discontinuing treatment. In this review, we summarize an array of clinically important characteristics of LAI and give a conceptual framework for understanding the pharmacokinetics of LAI.

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来源期刊

Ugeskrift for laeger Medicine-Medicine (all)

CiteScore

0.20

自引率

0.00%

发文量

345

期刊介绍： The Ulster Medical Journal is an international general medical journal with contributions on all areas of medical and surgical specialties relevant to a general medical readership. It retains a focus on material relevant to the health of the Northern Ireland population. The Honorary Editor would welcome offers of papers for publication. Prospective authors are invited to read the notice to contributors.