磁激光疗法对动脉高血压引起的糖尿病肾病患者的肾血液动力学研究

M. Evsina, Yulia М. Borzunova, A. Fedorov, A. Kaisinova, Viktor Yu. Gulyaev, I. I. Gaidamaka, V. Zelensky
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摘要

背景:近几十年来,全球慢性肾脏病患者人数逐渐增加,这既与心血管病变和 2 型糖尿病等相关疾病的实际发病率增加有关,也与患者预期寿命的延长有关。目的:在对动脉高血压引起的糖尿病肾病患者进行磁激光治疗的过程中,以这类患者的标准治疗为背景,评估肾血管的血液动力学。材料与方法:对 100 名动脉高血压引起的糖尿病肾病患者进行了随机对照试验。他们的平均年龄为 61.7 [52.8; 69.7]岁,动脉高血压病程为 24.1 [14.5; 36.1]年,2 型糖尿病病程为 16.6 [14.9; 19.1]年,糖尿病肾病病程为 6.1 [4.2; 8.9]年。除一般临床研究外,对照组患者(49 人)在使用标准药物治疗前后,以及主要组患者(51 人)在额外使用磁激光治疗后,还通过多普勒超声波检查了他们的肾血流量。结果:获得的数据表明,磁激光疗法对动脉高血压引起的糖尿病肾病患者的肾血管血液动力学有积极影响,中、小口径动脉的血流量均有所改善,这显然有助于肾实质毛细血管系统功能的正常化。结论:根据上述研究结果,我们建议在对动脉高血压引起的糖尿病肾病患者进行综合康复治疗时使用磁激光疗法,同时考虑到严格选择患者的标准。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Renal hemodynamics in patients with diabetic nephropathy caused by arterial hypertension using magnetic laser therapy
BACKGROUND: In recent decades, there has been a progressive increase in the number of patients with chronic kidney disease worldwide, which is associated with both an actual increase in the incidence of the disease, associated with cardiovascular pathology and type 2 diabetes mellitus, among other things, and an increase in the life expectancy of patients. AIM: To assess hemodynamics of renal vessels during a course of magnetic laser therapy with the patients suffering from diabetic nephropathy caused by arterial hypertension against the background of the standard of care for this category of patients. MATERIALS AND METHODS: There has been carried out a randomized controlled trial on 100 patients with diabetic nephropathy caused by arterial hypertension. Their average age was 61,7 [52,8; 69,7] years old, the duration of arterial hypertension ― 24,1 [14,5; 36,1], type 2 diabetes mellitus ― 16,6 [14,9; 19,1] and diabetic nephropathy ― 6,1 [4,2; 8,9] years. In addition to general clinical studies, the patients in the control group (49 people) before and after prescribing the standard medication, and in the main group (51 people) with additional use of magnetic laser therapy, had their renal blood flow examined by Doppler ultrasound. RESULTS: The obtained data indicate the positive effect of magnetic laser therapy with the patients suffering from diabetic nephropathy caused by arterial hypertension on the hemodynamics of renal vessels with improved blood flow in arteries of both medium and small caliber, which, in turn, apparently should contribute to the normalization of the function of the capillary system of the renal parenchyma. CONCLUSION: The results of the given study allow us to recommend the use of magnetic laser therapy in the complex rehabilitation treatment of the patients with diabetic nephropathy caused by arterial hypertension taking into account the criteria for their strict selection.
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