包含希夫碱和 2-氨基-4-甲基嘧啶的新型纳米级 V(III)、Fe(III) 和 Ni(II) 配合物:合成、性质和生物活性

IF 3 Q3 MATERIALS SCIENCE, BIOMATERIALS
Maged S. Al-Fakeh, Maha A. Alsikhan, J. Alnawmasi, Abdullah H. Alluhayb, Mona S. Al-Wahibi
{"title":"包含希夫碱和 2-氨基-4-甲基嘧啶的新型纳米级 V(III)、Fe(III) 和 Ni(II) 配合物:合成、性质和生物活性","authors":"Maged S. Al-Fakeh, Maha A. Alsikhan, J. Alnawmasi, Abdullah H. Alluhayb, Mona S. Al-Wahibi","doi":"10.1155/2024/9198129","DOIUrl":null,"url":null,"abstract":"A new synthesis of mixed ligand complexes vanadium(III), iron(III), and nickel(II), [M : L1 : L2], where L1 = Schiff base 2-((E)-((4-(((E)-benzylidene)amino)phenyl)imino)methyl)-naphthalene-1-ol (C24H18N2O) as for L2 = AMPY 2-amino-4-methyl pyrimidine (C5H7N3) were prepared in powder and investigated. Element analysis, molar conductivity, FT-IR, UV-vis, and magnetic susceptibility values have been acquired to describe the generated complexes. The values of vanadium(III), iron(III), and nickel(II) compounds are, respectively, 2.88 BM, 5.96 BM, and 2.92 BM, demonstrating that all compounds conform to the recommended octahedral geometry. Thermal gravimetric analysis (TGA) is used to further assess the complexes and establish the temperature stability and degradation of the metal complexes. The calculations abstracted from XRD patterns propose nanosized complexes (average size 29–50 nm). The microstructures of the samples have also been investigated by scanning electron microscopy (SEM). The disc diffusion method was used to assess and analyze the inhibition of the growth of compounds against harmful bacterial and fungal strains. The prepared complexes were tested against three strains of bacteria, one gram-positive strain (Bacillus subtilis), two gram-negative strains (Escherichia coli and Pseudomonas aeruginosa), and one fungus (Aspergillus fumigatus). The complexes inferred antimicrobial activity against the studied organisms. Specifically, vanadium(III) and nickel(II) are more effective than iron(III), making them promising drugs.","PeriodicalId":13704,"journal":{"name":"International Journal of Biomaterials","volume":null,"pages":null},"PeriodicalIF":3.0000,"publicationDate":"2024-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"New Nanosized V(III), Fe(III), and Ni(II) Complexes Comprising Schiff Base and 2-Amino-4-Methyl Pyrimidine: Synthesis, Properties, and Biological Activity\",\"authors\":\"Maged S. Al-Fakeh, Maha A. Alsikhan, J. Alnawmasi, Abdullah H. Alluhayb, Mona S. Al-Wahibi\",\"doi\":\"10.1155/2024/9198129\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A new synthesis of mixed ligand complexes vanadium(III), iron(III), and nickel(II), [M : L1 : L2], where L1 = Schiff base 2-((E)-((4-(((E)-benzylidene)amino)phenyl)imino)methyl)-naphthalene-1-ol (C24H18N2O) as for L2 = AMPY 2-amino-4-methyl pyrimidine (C5H7N3) were prepared in powder and investigated. Element analysis, molar conductivity, FT-IR, UV-vis, and magnetic susceptibility values have been acquired to describe the generated complexes. The values of vanadium(III), iron(III), and nickel(II) compounds are, respectively, 2.88 BM, 5.96 BM, and 2.92 BM, demonstrating that all compounds conform to the recommended octahedral geometry. Thermal gravimetric analysis (TGA) is used to further assess the complexes and establish the temperature stability and degradation of the metal complexes. The calculations abstracted from XRD patterns propose nanosized complexes (average size 29–50 nm). The microstructures of the samples have also been investigated by scanning electron microscopy (SEM). The disc diffusion method was used to assess and analyze the inhibition of the growth of compounds against harmful bacterial and fungal strains. The prepared complexes were tested against three strains of bacteria, one gram-positive strain (Bacillus subtilis), two gram-negative strains (Escherichia coli and Pseudomonas aeruginosa), and one fungus (Aspergillus fumigatus). The complexes inferred antimicrobial activity against the studied organisms. Specifically, vanadium(III) and nickel(II) are more effective than iron(III), making them promising drugs.\",\"PeriodicalId\":13704,\"journal\":{\"name\":\"International Journal of Biomaterials\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":3.0000,\"publicationDate\":\"2024-05-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Biomaterials\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1155/2024/9198129\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MATERIALS SCIENCE, BIOMATERIALS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Biomaterials","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/2024/9198129","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MATERIALS SCIENCE, BIOMATERIALS","Score":null,"Total":0}
引用次数: 0

摘要

一种新的混合配体钒(III)、铁(III)和镍(II)络合物[M : L1 : L2]的合成方法以粉末状制备并研究了 L1 = 席夫碱 2-((E)-((4-(((E)-亚苄基)氨基)苯基)亚氨基)甲基)-1-萘酚(C24H18N2O)和 L2 = AMPY 2-氨基-4-甲基嘧啶(C5H7N3)。对生成的配合物进行了元素分析、摩尔电导率、傅立叶变换红外光谱、紫外-可见光谱和磁感应强度测定。钒(III)、铁(III)和镍(II)化合物的数值分别为 2.88 BM、5.96 BM 和 2.92 BM,表明所有化合物都符合推荐的八面体几何形状。热重分析(TGA)用于进一步评估复合物,并确定金属复合物的温度稳定性和降解情况。根据 X 射线衍射图计算得出的结果表明,络合物的尺寸为纳米级(平均尺寸为 29-50 纳米)。样品的微观结构也通过扫描电子显微镜(SEM)进行了研究。盘扩散法用于评估和分析化合物对有害细菌和真菌菌株生长的抑制作用。制备的复合物针对三株细菌进行了测试,其中一株为革兰氏阳性菌(枯草芽孢杆菌),两株为革兰氏阴性菌(大肠杆菌和绿脓杆菌),一株为真菌(曲霉菌)。这些配合物对所研究的生物具有抗菌活性。具体来说,钒(III)和镍(II)比铁(III)更有效,因此是很有前途的药物。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
New Nanosized V(III), Fe(III), and Ni(II) Complexes Comprising Schiff Base and 2-Amino-4-Methyl Pyrimidine: Synthesis, Properties, and Biological Activity
A new synthesis of mixed ligand complexes vanadium(III), iron(III), and nickel(II), [M : L1 : L2], where L1 = Schiff base 2-((E)-((4-(((E)-benzylidene)amino)phenyl)imino)methyl)-naphthalene-1-ol (C24H18N2O) as for L2 = AMPY 2-amino-4-methyl pyrimidine (C5H7N3) were prepared in powder and investigated. Element analysis, molar conductivity, FT-IR, UV-vis, and magnetic susceptibility values have been acquired to describe the generated complexes. The values of vanadium(III), iron(III), and nickel(II) compounds are, respectively, 2.88 BM, 5.96 BM, and 2.92 BM, demonstrating that all compounds conform to the recommended octahedral geometry. Thermal gravimetric analysis (TGA) is used to further assess the complexes and establish the temperature stability and degradation of the metal complexes. The calculations abstracted from XRD patterns propose nanosized complexes (average size 29–50 nm). The microstructures of the samples have also been investigated by scanning electron microscopy (SEM). The disc diffusion method was used to assess and analyze the inhibition of the growth of compounds against harmful bacterial and fungal strains. The prepared complexes were tested against three strains of bacteria, one gram-positive strain (Bacillus subtilis), two gram-negative strains (Escherichia coli and Pseudomonas aeruginosa), and one fungus (Aspergillus fumigatus). The complexes inferred antimicrobial activity against the studied organisms. Specifically, vanadium(III) and nickel(II) are more effective than iron(III), making them promising drugs.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
International Journal of Biomaterials
International Journal of Biomaterials MATERIALS SCIENCE, BIOMATERIALS-
CiteScore
4.30
自引率
3.20%
发文量
50
审稿时长
21 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信