抗菌药的使用和耐药性:吉托尔地区公众知识和意识调查

PRASANNA LAKSHMI KAKARLA, PEDAPATIKASTURI, NELLORE SRIVANI, P. P. Babu
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摘要

目的:抗菌药耐药性(AMR)导致发病率和死亡率上升。世界卫生组织认为,抗菌药物耐药性是对人类健康的巨大威胁。印度是世界上细菌性疾病负担最重的国家,抗生素的使用十分猖獗。滥用和过度使用抗生素加速了 AMR 这一自然现象。正确使用抗生素的责任在于处方者和公众。生态、流行病学、文化和社会经济因素都会影响 AMR。本研究旨在加深对当前公众对抗菌药物、抗菌药物使用和 AMR 的认识以及相关常见行为的了解。研究方法:在 2022 年 1 月至 3 月期间,对前往奇托尔区蒂鲁帕蒂三级医院就诊的 400 名病人的护理人员进行了基于封闭式问卷的描述性面对面调查。调查对象包括年龄大于 18 岁的居民;不包括医护人员。采用世界卫生组织问卷收集数据,问卷由两部分组成。结果:抗生素的使用非常普遍,70%的受访者在过去 6 个月中至少使用过一次抗生素。许多受访者误认为头痛(42%)和感冒(38%)需要使用抗生素。只有 66% 的受访者知道要服用完整疗程的抗生素。26% 的受访者从未听说过抗生素耐药性这一术语。51% 的参与者不知道耐抗生素细菌会在人群中传播。所有受访者都认为定期洗手很有帮助。结论调查发现,公众在这方面的知识存在巨大差距,同时还存在各种错误观念和误解。当务之急是尽快消除这些差距,以挽救现有抗生素的效力。造成误解的原因和消除误解的方法需要进一步研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
ANTIMICROBIAL USE AND RESISTANCE: SURVEY OF KNOWLEDGE AND AWARENESS OF GENERAL PUBLIC IN CHITTOOR DISTRICT
Objective: Antimicrobial resistance (AMR) leads to increased morbidity and mortality. WHO identified AMR as great threat to human health. India with highest bacterial disease burden in the world has rampant antibiotic usage. Natural phenomenon AMR is accelerated by the misuse and overuse of antibiotics. The responsibility of proper usage lies with both the prescribers and general public. Ecological, epidemiological, cultural and socioeconomic factors influence AMR. This study aims to enhance understanding of current public awareness and common behaviors related to antimicrobials, their use and AMR. Methods: Descriptive closed-questionnaire-based face-to-face survey was conducted between January to March 2022 among 400 attendants of patients visiting the tertiary care hospital at Tirupati, Chittoor District. Residents aged>18 y were included; health care providers excluded. Data was collected using WHO questionnaire consisting of two parts. Results: There is widespread antibiotic usage-70% of participants used at least once in past 6 mo. Many respondents were mistaken that head ache (42%) and cold (38%) require antibiotics. Only 66% of respondents knew to take full course of antibiotics. 26% of respondents never heard of antibiotic resistance terminology. 51% of participants had no idea that antibiotic-resistant bacteria can spread among persons. All the respondents agreed that regular hand washing is helpful. Conclusion: Huge knowledge gaps were found along with various misconceptions and misunderstandings in the public. It is imperative to address these gaps as soon as possible to save the potency of available antibiotics. Reasons for misconceptions and ways to dispel them need further studies.
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