墨西哥早发重度子痫前期孕产妇不良预后预测：全PIERS模型的验证

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-05-15 DOI:10.1155/2024/5520312

Eduardo Ponce Nájera, Marcela Montoya Hinojosa, Rogelio Armando Lozano Galván, Diego González Oropeza

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引用次数: 0

摘要

目的验证全 PIERS 模型在预测我国早发重度子痫前期产妇不良预后方面的有效性。方法：回顾性队列研究。回顾性队列研究。我们对 130 名在墨西哥新莱昂州一家二级医院接受治疗的重度早发型子痫前期妇女应用了全 PIERS 模型。我们通过 AUROC 验证了全 PIERS 模型的分辨能力。结果。应用于本研究数据的全 PIERS 模型具有良好的判别能力，其 AUC 为 0.718（95% CI 0.515-0.921；P=0.017）。7.95分界点被认为是诊断效果最好的分界点，尤登指数最高，对并发症发生的敏感性为54.5%，特异性为99.2%。结论全PIERS模型可以预测我院重度早发型子痫前期产妇在入院48小时内的不良预后。

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Prediction of Adverse Maternal Outcomes in Women with Early-Onset Preeclampsia with Severe Features in Mexico: Validation of the Full-PIERS Model

Objective. Validate the full-PIERS model in predicting adverse maternal outcomes in women with early-onset preeclampsia with severe features in our population. Methods. Retrospective cohort study. We applied the full-PIERS model on 130 women with severe early-onset preeclampsia who were treated at a second-level hospital in Nuevo León, México. We validated the full-PIERS model in its ability to discriminate through the AUROC. Results. The full-PIERS model applied to the data obtained in our study had good discrimination, revealing an AUC of 0.718 (95% CI 0.515–0.921; P=0.017). A cut-off of 7.95 was identified as the cut-off point with the best diagnostic performance, with the highest Youden index, presenting a sensitivity of 54.5% and specificity of 99.2% for the development of complications. Conclusion. The full-PIERS model can predict adverse maternal outcomes in women admitted to our hospital with severe early-onset preeclampsia within 48 hours of admission.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.