严重外周溃疡性角膜炎与扁平苔藓并存。病例报告

Hamza Lazaar, T. Boutaj, M. Sefrioui, Najoua ElMoubarik, B. Azarkan, Saad Benchekroun, Abdellah Amazouzi, Noureddine Boutimzine, Lalla Cherkaoui Ouafa
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引用次数: 0

摘要

扁平苔藓的眼部受累非常少见,主要影响眼睑、结膜,角膜也较少见。周围溃疡性角膜炎(PUK)是角膜扁平苔藓的一种罕见亚型,文献中仅有过一次报道。 我们报告了一名 34 岁男子的详细病例,他被确诊为皮肤扁平苔藓,但却患上了严重的周围溃疡性角膜炎(PUK),这是扁平苔藓的一种罕见眼部表现。尽管最初使用皮质类固醇激素后病情有所恶化,但在两个月内使用局部环孢素和硫唑嘌呤后,PUK 成功缓解,但最终视力仅限于光感。 据我们所知,严重周围性溃疡性角膜炎和扁平苔藓并存的病例非常罕见。任何伴有皮肤黏膜表现的周围性溃疡性角膜炎病例都应考虑扁平苔藓 环孢素和硫唑嘌呤对此类病例的有效治疗和良好疗效至关重要。 本病例旨在说明在出现任何周围性溃疡性角膜炎时进行皮肤科检查的重要性,同时也揭示了这种罕见的眼扁平苔藓的治疗难点和预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Coexistence of severe peripheral ulcerative keratitis and lichen planus. Case Report
Ocular involvement in lichen planus is highly uncommon, primarily affecting the eyelids, conjunctiva, and less frequently, the cornea. Peripheral Ulcerative Keratitis (PUK), a rare subtype form of corneal lichen planus, has been reported only once in the literature. We report details of a 34-year-old man with confirmed cutaneous lichen planus who developed severe peripheral ulcerative keratitis (PUK), a rare ocular manifestation of lichen planus. Despite initial worsening with corticosteroids, successful resolution of PUK was achieved with topical Cyclosporin and azathioprine over two months but with a final visual acuity limited to light perception. To the best of our knowledge, very rare cases have been reported of the Coexistence of Severe Peripheral Ulcerative Keratitis and Lichen Planus. Lichen planus should be considered in any case of peripheral ulcerative keratitis associated with cutaneous-mucosal manifestations Cyclosporin and azathioprine are crucial for effective management and favorable outcomes in such cases. This case aims to show the importance of dermatological examination in the presence of any peripheral ulcerative keratitis. it also sheds light on the therapeutic difficulties and the prognosis of this rare form of ocular lichen planus.
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