口红中的铅(Pb)含量会对儿童健康造成危害吗?一项风险评估研究。

Demir Mesut Öztaş, Onur Kenan Ulutaş, Aysel Berkkan
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引用次数: 0

摘要

背景:口红中的铅(Pb)含量以及消费者终生接触铅可能导致的严重后果是公众关注的一个重要问题。因此,研究强调铅暴露没有安全水平:方法:从土耳其市场上的 10 个不同品牌中,共挑选出 25 种固体、亮光和膏状口红,并将其分为两个不同的价格区间。为了评估儿童血液中的铅含量,采用了美国环境保护局的 "暴露吸收生物动力学模型"。为了评估儿童和成人长期使用口红的健康风险,我们计算了最坏情况下的每日口腔全身接触水平,并与口红的最大允许剂量水平进行了比较。对于终生风险评估,假定从 7 岁开始接触,并采用了四种不同的接触情景:结果:口红的平均含铅量在高价和低价口红组之间存在显著的统计差异。所使用口红的每日铅含量和终生铅暴露总风险均低于可接受的风险水平,但长期使用产品并对金属含量进行例行监测,对于敏感和意外暴露人群至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Do lead (Pb) content of lipsticks expose a health risk to children? A risk assessment study.

Background: Lead (Pb) content in lipsticks and potential life-long exposure of which might cause severe effects in consumers are an important concern for public. Thus, studies emphasize that lead exposure has no safe levels.

Methods: From 10 different brands, in total, 25 solid, gloss and creamy lipsticks are deployed from Turkish markets that are also categorized in two different price ranges. In order to evaluate the blood Pb levels in children, the United States Environmental Protection Agency's 'Exposure Uptake Biokinetic Model' is utilized. To assess the health risk of chronic usage both for children and adults, oral daily systemic exposure levels are calculated with the worst-case scenario and are compared with Maximum Allowable Dose Level for lipsticks. For lifetime risk assessment, exposure is assumed to start by age 7, and four different exposure scenarios have been deployed.

Results: The mean lead content of lipsticks shows significant statistical differences between the high- and low-priced lipstick groups. Daily level and total risk for lifetime Pb exposure from deployed lipsticks are below the acceptable risk levels but long-worn usage of products with routine monitoring of metal content is crucial for sensitive and unintended exposure groups.

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