癫痫犬的弓形虫和犬新孢子虫感染。

IF 1.7 2区 农林科学 Q2 VETERINARY SCIENCES
G. Morganti, G. Rigamonti, M. C. Marchesi, G. Maggi, G. Angeli, I. Moretta, L. Brustenga, M. Diaferia, F. Veronesi
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引用次数: 0

摘要

目的:对人类的研究表明,弓形虫(一种原生动物寄生虫)在癫痫发作中起着重要作用。本研究旨在调查弓形虫和犬鼻疽与狗癫痫之间的血清学相关性:在佩鲁贾大学兽医教学医院的病历数据库中搜索了通过 IFAT 进行淋病双球菌和犬细小病毒血清学检测并符合特定纳入标准的犬只。根据临床诊断为癫痫或患有不同疾病的狗进行了分层:结果:共纳入 128 只狗,其中 64 只患有癫痫,64 只没有癫痫的临床症状。64只癫痫犬中有17只(26.6%;95% CI:15.7%至37.4%)和64只非癫痫犬中有21只(32.8%;95% CI:21.3%至44.3%)对淋病双球菌检测呈阳性。八只癫痫犬(12.5%;95% CI:4.4% 至 20.6%)和三只非癫痫犬(4.7%;95% CI:0% 至 9.9%)对犬结核菌检测呈阳性。癫痫犬和非癫痫犬的淋病双球菌或N. caninum血清反应率没有明显的统计学差异:临床意义:所获得的结果似乎并不支持淋病双球菌和犬细小病毒是狗癫痫的致病因子。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Toxoplasma gondii and Neospora caninum infection in epileptic dogs

Objectives

Studies in humans have demonstrated the role of Toxoplasma gondii, a protozoan parasite, in epileptic seizures. This study aimed to investigate the serological correlation between T. gondii and N. caninum and epilepsy in dogs.

Materials and Methods

The medical record database of the Veterinary Teaching Hospital, University of Perugia, was searched for dogs serologically tested by IFAT for T. gondii and N. caninum and following specific inclusion criteria. Dogs were stratified by having a clinical diagnosis of epilepsy or suffering different conditions.

Results

One-hundred and twenty-eight dogs were included, 64 with epilepsy and 64 without clinical signs of epilepsy. Seventeen of the 64 epileptic dogs (26.6%; 95% CI: 15.7% to 37.4%) and twenty-one of the 64 non-epileptic dogs (32.8%; 95% CI: 21.3% to 44.3%) tested positive for T. gondii. Eight of the epileptic dogs (12.5%; 95% CI: 4.4% to 20.6%) and three of the non-epileptic dogs (4.7%; 95% CI: 0% to 9.9%) tested positive for N. caninum. There was no statistically significant difference in the rate of T. gondii or N. caninum seroreactivity between epileptic and non-epileptic dogs.

Clinical Significance

The results obtained do not seem to support the role of T. gondii and N. caninum as causative agents of dog epilepsy.

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来源期刊
Journal of Small Animal Practice
Journal of Small Animal Practice 农林科学-兽医学
CiteScore
3.30
自引率
6.20%
发文量
117
审稿时长
12-24 weeks
期刊介绍: Journal of Small Animal Practice (JSAP) is a monthly peer-reviewed publication integrating clinical research papers and case reports from international sources, covering all aspects of medicine and surgery relating to dogs, cats and other small animals. These papers facilitate the dissemination and implementation of new ideas and techniques relating to clinical veterinary practice, with the ultimate aim of promoting best practice. JSAP publishes high quality original articles, as well as other scientific and educational information. New developments are placed in perspective, encompassing new concepts and peer commentary. The target audience is veterinarians primarily engaged in the practise of small animal medicine and surgery. In addition to original articles, JSAP will publish invited editorials (relating to a manuscript in the same issue or a topic of current interest), review articles, which provide in-depth discussion of important clinical issues, and other scientific and educational information from around the world. The final decision on publication of a manuscript rests with the Editorial Board and ultimately with the Editor. All papers, regardless of type, represent the opinion of the authors and not necessarily that of the Editor, the Association or the Publisher. The Journal of Small Animal Practice is published on behalf of the British Small Animal Veterinary Association and is also the official scientific journal of the World Small Animal Veterinary Association
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