Simon Sirtl, Eric Hohmann, Georg Beyer, Jacob Hamm, Albrecht Neesse, Christoph Ammer-Herrmenau
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引用次数: 0
摘要
背景/目的：季节性是否是影响急性胰腺炎（AP）发病率的一个因素是一个研究不足的领域。迄今为止，文献对是否能检测到季节性发病高峰，特别是胆源性胰腺炎的季节性发病高峰给出了相互矛盾的答案：根据 ICD-10 出院代码，确定了 2016 年至 2022 年期间德国两家三级转诊中心的所有 AP 病例。采用χ2检验拟合优度，检验AP入院病例的月度分布和季节分布的显著差异：结果：共纳入 3597 例 AP 病例。我们观察到 5 月至 7 月的特发性和胆源性病例明显增多（p 值分别为 0.041 和 0.027）。此外，大多数由药物诱发的 AP 病例都是在冬季发现的（p 值为 0.006）。此外，夏季和秋季是酒精诱发胰腺炎的高峰期（p 值为 0.038）：我们的数据表明，某些病因导致的胰腺炎发病率受季节影响。
The four seasons of pancreatitis - Etiology of acute pancreatitis during the course of the year.
Background/objectives: Whether seasonality is a factor that influences the incidence of acute pancreatitis (AP) is an under-investigated area. If seasonal incidence peaks can be detected, specifically with regard to biliary pancreatitis, has so far been answered in contradictory ways in the literature.
Methods: All AP cases from two tertiary German referral centers were identified between 2016 and 2022 based on ICD-10 discharge codes. The χ2 test for goodness of fit was applied to test significant differences in monthly and seasonal distributions of AP admissions.
Results: In total, 3597 AP cases were included. We observed significantly more idiopathic and biliary cases in May to July (p-values 0.041 and 0.027, respectively). Furthermore, most drug-induced APs were identified during the winter months (p-value 0.006). Moreover, there was a significant peak of alcohol-induced pancreatitis in summer and fall (p-value 0.038).
Conclusions: Our data indicate a seasonal impact on AP incidences for certain etiologies.
期刊介绍：
Die Zeitschrift für Gastroenterologie ist seit über 50 Jahren die führende deutsche Fachzeitschrift auf dem Gebiet der Gastroenterologie. Sie richtet sich an Gastroenterologen und alle anderen gastroenterologisch interessierten Ärzte. Als offizielles Organ der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten sowie der Österreichischen Gesellschaft für Gastroenterologie und Hepatologie informiert sie zuverlässig und aktuell über die wichtigen Neuerungen und Entwicklungen in der Gastroenterologie.
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