用于实时葡萄糖监测的电化学传感器的进展

IF 3.5 Q2 CHEMISTRY, ANALYTICAL
Md. Harun-Or-Rashid, Most. Nazmin Aktar, Veronica Preda and Noushin Nasiri
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引用次数: 0

摘要

技术进步正在彻底改变全世界的糖尿病护理,尤其是在血糖监测领域。传统的血糖监测既有创又繁琐,现在正向微创方法转变,从而提高了患者的生活质量,降低了与低血糖和高血糖相关的风险。以汗液和组织间液为重点的可穿戴生物传感器为早期疾病检测和个性化护理点检测提供了新的途径。本综述全面概述了可穿戴汗液传感器的最新进展,包括历史观点、电化学传感机制、材料进步以及纳米材料在提高传感器性能方面的作用。通过研究葡萄糖监测设备的演变过程和重点介绍市售设备,该综述强调了电化学传感器在葡萄糖监测中的广泛用途。文章详细讨论了酶和非酶传感机制、电位传感器、安培/伏安传感器、离子选择性电极和生物传感器,以及用于优化传感器性能的各种材料。人们对纳米材料传感器平台的兴趣日益浓厚,这标志着基于汗液的葡萄糖监测前景广阔,对个性化医疗保健和疾病管理具有潜在影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Advances in electrochemical sensors for real-time glucose monitoring

Advances in electrochemical sensors for real-time glucose monitoring

Advances in electrochemical sensors for real-time glucose monitoring

Technological advancements are revolutionizing diabetic care worldwide, particularly in the realm of glucose monitoring. Traditionally invasive and cumbersome, glucose monitoring is shifting towards less invasive methods, enhancing patient quality of life and reducing risks associated with hypo- and hyperglycemia. Wearable biosensors, focusing on sweat and interstitial fluid, offer novel avenues for early disease detection and personalized point-of-care testing. This review paper provides a comprehensive overview of recent strides in wearable sweat sensors, including historical perspectives, electrochemical sensing mechanisms, material advancements, and the role of nanomaterials in enhancing sensor performance. By examining the evolution of glucose monitoring devices and highlighting commercially available devices, the review underscores the wide-ranging utility of electrochemical sensors in glucose monitoring. Enzymatic and non-enzymatic sensing mechanisms, potentiometric, amperometric/voltammetric sensors, ion-selective electrodes, and biosensors are discussed in detail, alongside various materials employed to optimize sensor performance. The burgeoning interest in nanomaterial-enabled sensor platforms signifies a promising future for sweat-based glucose monitoring, with potential implications for personalized healthcare and disease management.

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