利用表面增强拉曼光谱 (SERS) 研究 N-杂环碳烯银络合物 [双（1,3-二戊基-1,3-二氢-2-咪唑-2-亚基）银 (I) 六氟磷酸盐 (V)] 的合成、表征和 DNA 结合力

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-05-05 DOI:10.1080/00032719.2024.2346276

Fareeha Zafar, Shazra Ishtiaq, Muhammad Irfan Majeed, Najah Alwadie, Muhammad Rizwan Javed, Haq Nawaz, Muhammad Adnan Iqbal, Ayesha Ashraf, Umer Farooq, Ahmad Hassan, Muhammad Zohaib, Zainab Shoukat

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引用次数: 0

摘要

银有机金属化合物能有效靶向癌细胞中的 DNA，并通过抑制 DNA 复制来阻止其生长。这些化合物的特殊性质有助于它们作为药物发挥作用...

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Synthesis, Characterization and DNA Binding Study of Silver N-Heterocyclic Carbene Complex [Bis (1,3-Dipentyl-1,3-Dihydro-2-Imidazole-2-Ylidene) Silver (I) hexafluorophosphate (V)] by Surface-Enhanced Raman Spectroscopy (SERS)

The silver organometallic compounds favorably target DNA in cancerous cells and stop their growth by inhibiting DNA replication. Specific properties of these compounds help in their action as drugs...

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.