基于植物提取物的微囊药物的生产前景(综述)

IF 0.8 4区 医学 Q4 CHEMISTRY, MEDICINAL
O. A. Semkina, O. M. Beloshapkina, M. A. Dzhavakhyan
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引用次数: 0

摘要

综述了用于开发和生产具有药理活性的药物和活性物质的植物提取物微胶囊技术的特殊性。文章介绍了一些植物提取物微囊化方法的优点:乳化(分散)、共凝、离子凝胶、喷雾和冷冻干燥、溶剂蒸发、挤压、流化床微囊化。确定了选择植物提取物封装方法的参数。阐述了植物提取物微胶囊技术的可能前景。利用电子数据库 PubMed、e-Library 和 CyberLeninka 以及谷歌学术搜索引擎分析了国内外公共领域的文献资料。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Prospects for Production of Microencapsulated Medicines Based on Plant Extracts (Review)

Prospects for Production of Microencapsulated Medicines Based on Plant Extracts (Review)

Material devoted to the peculiarities of plant extract microencapsulation used for the development and production of drugs and active substances with pharmacological activity is reviewed. The advantages of some microencapsulation methods of plant extracts are shown: emulsification (dispersion), coacervation, ionic gelation, spray and freeze drying, solvent evaporation, extrusion, fluidized bed microencapsulation. The parameters for choosing an encapsulation method for plant extracts were determined. Possible prospects for microencapsulation technology of plant extracts were described. Domestic and foreign literature sources in the public domain were analyzed using the electronic databases PubMed, e-Library, and CyberLeninka and Google Scholar search engine.

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来源期刊
Pharmaceutical Chemistry Journal
Pharmaceutical Chemistry Journal CHEMISTRY, MEDICINAL-PHARMACOLOGY & PHARMACY
CiteScore
1.30
自引率
22.20%
发文量
226
审稿时长
3-8 weeks
期刊介绍: Pharmaceutical Chemistry Journal is a monthly publication devoted to scientific and technical research on the creation of new drugs and the improvement of manufacturing technology of drugs and intermediates. International contributors cover the entire spectrum of new drug research, including: methods of synthesis; results of pharmacological, toxicological, and biochemical studies; investigation of structure - activity relationships in prediction of new compounds; methods and technical facilities used; and problems associated with the development of ecologically safe and economically feasible methods of industrial production. In addition, analytical reviews of the international literature in the field provide coverage of the most recent developments around the world. Pharmaceutical Chemistry Journal is a translation of the Russian journal Khimiko-Farmatsevticheskii Zhurnal. The Russian Volume Year is published in English from April. All articles are peer-reviewed.
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