Abdul Rehman Rashid, Khadija- Tul-Kubra, Ayesha Latif
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引用次数: 0
摘要
烧伤是一种使人衰弱、破坏性极大的急症,会带来许多生理和心理上的后遗症。烧伤伤口处理的基本步骤包括清洁/伤口清创、局部使用抗菌剂和患处包扎。本研究的目的是比较水纤维银敷料和 1%磺胺嘧啶银敷料在治疗小儿烧伤患者伤口愈合方面的效果。在获得伦理批准后,264 名患者被纳入研究并分为两组。由经验丰富的小儿外科医生检查伤口是否重新上皮化,并在 15 天后标注疗效。在 264 名登记患者中,148 名(56.06%)为男性,116 名(43.94%)为女性。患者的平均年龄为(3.73±2.34)岁。215 名患者(81.4%)的烧伤类型为烫伤,49 名患者(18.6%)的烧伤类型为火焰烧伤。185例(70.08%)患者的烧伤深度为二度,79例(29.92%)患者的烧伤深度为三度。平均 TBSA 为 19.93±9.62%。在 A 组中,91(68.9%)名患者获得了疗效,而在 B 组中,73(55.3%)名患者获得了疗效。
Comparison of hydro-fiber silver dressing and 1% silver sulfadiazine dressing for treatment of pediatric burns.
Burn is a debilitating and devastating emergency with many physical and psychological sequelae. Essential steps in burn wound management include cleansing/wound debridement, application of topical antimicrobial and dressing of affected body areas. Objective of this study is comparison in effectiveness of Hydro-fiber Silver dressing and 1% silver sulfadiazine dressing in management of pediatric burn patients in terms of wound healing. After ethical approval, 264 patients were enrolled and divided into two groups. Patients were managed with hydro-fiber silver dressing in group A and 1% silver sulfadiazine dressing in group B. An experienced pediatric surgeon examined the wounds for re epithelialization and efficacy was labeled after 15 days. Out of 264 enrolled patients 148(56.06%) were males and 116(43.94%) were females. Mean age of patients was 3.73±2.34 years. Type of burn was Scald in 215(81.4%) patients and flame in 49(18.6%). Depth of burn was 2nd degree in 185(70.08%) patients and 3rd degree in 79(29.92%) patients. Mean TBSA was 19.93±9.62%. In group A the efficacy was achieved in 91(68.9%) patients whereas in group B the efficacy was achieved in 73(55.3%) patients (p-value<0.05). Hydro-fiber Silver dressing is significantly more efficacious as compared to 1% silver sulfadiazine dressing for treatment of pediatric burn.
期刊介绍:
Pakistan Journal of Pharmaceutical Sciences (PJPS) is a peer reviewed multi-disciplinary pharmaceutical sciences journal. The PJPS had its origin in 1988 from the Faculty of Pharmacy, University of Karachi as a biannual journal, frequency converted as quarterly in 2005, and now PJPS is being published as bi-monthly from January 2013.
PJPS covers Biological, Pharmaceutical and Medicinal Research (Drug Delivery, Pharmacy Management, Molecular Biology, Biochemical, Pharmacology, Pharmacokinetics, Phytochemical, Bio-analytical, Therapeutics, Biotechnology and research on nano particles.