Diego Romário-Silva, Marcelo Franchin, Severino Matias Alencar, Bruno Bueno-Silva, Janaína de Cássia Orlandi Sardi, Andréa Cristina Barbosa da Silva, Fabiane Cruz-Vieira, Priscila Vieira da Silva, Pedro Luiz Rosalen
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Antimicrobial and antibiofilm activities of Brazilian organic honey against oral microorganisms.
Objective: To evaluate the antimicrobial activity of Brazilian honeys against oral microorganisms.
Design: Organic honeys (OH-1 to OH-8) were diluted (%-w/v) and sterilized by filtration. Antimicrobial activity was defined by determining MIC and CBM against oral Streptococcus. The component responsible for the antimicrobial action was defined by a catalase assay. Antibiofilm activity was evaluated against the monospecies biofilm of Streptococcus mutans (ATCC 700610).
Results: OHs showed antimicrobial activity principally OH-1, OH-2, OH-3, and OH-7 with MIC values ranging between 10 and 25%. The mechanism of action occurs mainly by hydrogen peroxide produced by honey enzymes. OH-1, OH-2, and OH-7 showed total biofilm destruction at low concentrations.
Conclusion: Brazilian honeys have promising antimicrobial and antibiofilm activity with the potential to control oral microbiota.
期刊介绍：
The Brazilian Journal of Microbiology is an international peer reviewed journal that covers a wide-range of research on fundamental and applied aspects of microbiology.
The journal considers for publication original research articles, short communications, reviews, and letters to the editor, that may be submitted to the following sections: Biotechnology and Industrial Microbiology, Food Microbiology, Bacterial and Fungal Pathogenesis, Clinical Microbiology, Environmental Microbiology, Veterinary Microbiology, Fungal and Bacterial Physiology, Bacterial, Fungal and Virus Molecular Biology, Education in Microbiology. For more details on each section, please check out the instructions for authors.
The journal is the official publication of the Brazilian Society of Microbiology and currently publishes 4 issues per year.
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