Haiyang Wang , Jing Lu , Mingjiang Wu , Yumei Zhang
{"title":"温和条件下 K2CO3 催化的高效 O 和 N-酰化反应","authors":"Haiyang Wang , Jing Lu , Mingjiang Wu , Yumei Zhang","doi":"10.1016/j.tgchem.2024.100041","DOIUrl":null,"url":null,"abstract":"<div><p>An eco-friendly, mild and efficient acylation of various nucleophiles with alkenyl carboxylates via inorganic base catalysis is described. Among five inorganic base species examined, K<sub>2</sub>CO<sub>3</sub> was proved to be the most efficient catalyst for the acylation. A broad variety of acylated products were achieved within 15 min at room temperature in high yields. In addition, we found that the 3-position of indoles should have a suitable substituent group under this procedure.</p></div>","PeriodicalId":101215,"journal":{"name":"Tetrahedron Green Chem","volume":"3 ","pages":"Article 100041"},"PeriodicalIF":0.0000,"publicationDate":"2024-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773223124000062/pdfft?md5=3dee0134e624e47cdb0172e74320ed1d&pid=1-s2.0-S2773223124000062-main.pdf","citationCount":"0","resultStr":"{\"title\":\"K2CO3-catalyzed highly efficient O and N-acylation under mild conditions\",\"authors\":\"Haiyang Wang , Jing Lu , Mingjiang Wu , Yumei Zhang\",\"doi\":\"10.1016/j.tgchem.2024.100041\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>An eco-friendly, mild and efficient acylation of various nucleophiles with alkenyl carboxylates via inorganic base catalysis is described. Among five inorganic base species examined, K<sub>2</sub>CO<sub>3</sub> was proved to be the most efficient catalyst for the acylation. A broad variety of acylated products were achieved within 15 min at room temperature in high yields. In addition, we found that the 3-position of indoles should have a suitable substituent group under this procedure.</p></div>\",\"PeriodicalId\":101215,\"journal\":{\"name\":\"Tetrahedron Green Chem\",\"volume\":\"3 \",\"pages\":\"Article 100041\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-05-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2773223124000062/pdfft?md5=3dee0134e624e47cdb0172e74320ed1d&pid=1-s2.0-S2773223124000062-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Tetrahedron Green Chem\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2773223124000062\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Tetrahedron Green Chem","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2773223124000062","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
K2CO3-catalyzed highly efficient O and N-acylation under mild conditions
An eco-friendly, mild and efficient acylation of various nucleophiles with alkenyl carboxylates via inorganic base catalysis is described. Among five inorganic base species examined, K2CO3 was proved to be the most efficient catalyst for the acylation. A broad variety of acylated products were achieved within 15 min at room temperature in high yields. In addition, we found that the 3-position of indoles should have a suitable substituent group under this procedure.