早产与儿童和成人肾小球疾病不良后果的关系

IF 8.5 1区医学 Q1 UROLOGY & NEPHROLOGY

Clinical Journal of the American Society of Nephrology Pub Date : 2024-08-01 Epub Date: 2024-05-10 DOI:10.2215/CJN.0000000000000475

Jaya S Isaac, Jonathan P Troost, Yujie Wang, Kelly Garrity, Frederick Kaskel, Rasheed Gbadegesin, Kimberly J Reidy

引用次数: 0

摘要

背景：虽然对肾病综合征患儿的一些研究表明，早产儿的预后比足月儿差，但关于早产与成年肾小球疾病预后的关系却鲜有数据。早产儿肾小球疾病患者的心血管预后尚不清楚：我们对治疗肾小球肾病（CureGN）队列中的参与者进行了横断面和纵向分析。早产儿共有 2,205 名足月儿和 235 名早产儿。APOL1风险等位基因在早产儿中更为常见。在 CureGN 的参与者中，早产的儿童比成人多：12.8% 对 7.69%（结论：早产是导致糖尿病的风险因素：早产是这个由患有肾小球疾病的儿童和成人组成的异质队列中出现不良后果的一个风险因素。早产儿更有可能具有 APOL1 高危基因型和 FSGS。在对FSGS和APOL1风险状况进行调整后的分析中，早产儿的肾病缓解率更低，进展更快。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Association of Preterm Birth with Adverse Glomerular Disease Outcomes in Children and Adults.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Clinical Journal of the American Society of Nephrology 医学-泌尿学与肾脏学

CiteScore

12.20

自引率

3.10%

发文量

514

审稿时长

3-6 weeks

期刊介绍： The Clinical Journal of the American Society of Nephrology strives to establish itself as the foremost authority in communicating and influencing advances in clinical nephrology by (1) swiftly and effectively disseminating pivotal developments in clinical and translational research in nephrology, encompassing innovations in research methods and care delivery; (2) providing context for these advances in relation to future research directions and patient care; and (3) becoming a key voice on issues with potential implications for the clinical practice of nephrology, particularly within the United States. Original manuscript topics cover a range of areas, including Acid/Base and Electrolyte Disorders, Acute Kidney Injury and ICU Nephrology, Chronic Kidney Disease, Clinical Nephrology, Cystic Kidney Disease, Diabetes and the Kidney, Genetics, Geriatric and Palliative Nephrology, Glomerular and Tubulointerstitial Diseases, Hypertension, Maintenance Dialysis, Mineral Metabolism, Nephrolithiasis, and Transplantation.