研究锰锌对成年斑马鱼(Danio rerio)的毒性。

IF 2.3 4区 医学 Q3 ENVIRONMENTAL SCIENCES
Ellen Jaqueline Mendes, Samara Cristina Mazon, Isabella Bodanese Marsaro, Maria Eduarda Hermes, Adrieli Sachett, Kanandra Taisa Bertoncello, Fernando Rafael de Moura, Flavio Manoel Rodrigues da Silva Júnior, Liz Girardi Müller, Cássia Alves Lima-Rezende, Anna Maria Siebel
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引用次数: 0

摘要

随着世界人口的不断增长和对粮食的持续需求,农业变得越来越重要。为了避免生产损失,农民通常会使用杀虫剂。代森锰锌是一种用于农业的杀真菌剂,因为这种化合物能有效对付危害农作物的真菌。然而,这种杀菌剂也可能对土壤和水中的非目标生物造成损害。因此,本研究旨在以成年斑马鱼(Danio rerio)为模型,研究暴露于曼可噻对其存活率、运动活性、行为和氧化状态的影响。实验组分别为阴性对照组、阳性对照组和曼库扎布(0.3;1.02;3.47;11.8 或 40 微克/升)组。斑马鱼暴露于相应的处理中 96 小时。接触锰锌不会明显改变斑马鱼的存活率和氧化状态。当浓度为 11.8 μg/L 时,杀真菌剂会导致动物的运动模式发生变化。研究结果表明,环境中存在的代森锰锌可能会导致成年斑马鱼的运动模式发生改变,进而破坏动物的先天防御机制。在自然界中,锰锌对非目标生物的这种影响可能会导致不利的种群影响和生态失衡。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Investigation on the mancozeb toxicity in adult zebrafish (Danio rerio).

Agriculture has gained increasing importance in response to the continuous growth of the world population and constant need for food. To avoid production losses, farmers commonly use pesticides. Mancozeb is a fungicide used in agriculture as this compound is effective in combating fungi that harm crops. However, this fungicide may also produce damage to non-target organisms present in soil and water. Therefore, this study aimed to investigate the influence of exposure to mancozeb on survival rate, locomotor activity, behavior, and oxidative status utilizing adult zebrafish (Danio rerio) as a model following exposure to environmentally relevant concentrations of this pesticide. The experimental groups were negative control, positive control, and mancozeb (0.3; 1.02; 3.47; 11.8 or 40 μg/L). Zebrafish were exposed to the respective treatments for 96 hr. Exposure to mancozeb did not markedly alter survival rate and oxidative status of Danio rerio. At a concentration of 11.8 μg/L, the fungicide initiated changes in locomotor pattern of the animals. The results obtained suggest that the presence of mancozeb in the environment might produce locomotor alterations in adult zebrafish, which subsequently disrupt the animals' innate defense mechanisms. In nature, this effect attributed to mancozeb on non-target organisms might result in adverse population impacts and ecological imbalance.

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来源期刊
CiteScore
5.20
自引率
19.20%
发文量
46
审稿时长
8-16 weeks
期刊介绍: The Journal of Toxicology and Environmental Health, Part A , Current Issues is an authoritative journal that features strictly refereed original research in the field of environmental sciences, public and occupational health, and toxicology.
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