Le syndrome d’entérocolite induite par les protéines alimentaires (SEIPA) en Alsace : description d’une cohorte de 48 patients et analyse des spécificités régionales des aliments déclencheurs

The Food Protein-Induced Enterocolitis Syndrome (FPIES) is a non-IgE-mediated food allergy, primarily manifesting in young children through vomiting. There are numerous differences regarding the implicated foods depending on the country and population studied. The study focused on a regional cohort of 48 children with FPIES in France, aiming to identify the most common triggers and provide appropriate dietary advice to families. Data were collected through telephone interviews with the families of FPIES patients. The results revealed that cow's milk was the most frequent trigger (67%), followed by egg (21%), beef, and fish (10% each). A correlation between reactions to beef and cow's milk was observed. The most commonly reported symptoms were vomiting, followed by abdominal pain, pallor, and diarrhea. IgE sensitization was present in 19% of tested children, with no statistically significant influence on FPIES recovery. In conclusion, this study emphasizes the significance of regional peculiarities in FPIES trigger foods and suggests that dietary recommendations should be adjusted accordingly.