[合成大麻素的毒理学]。

Youssef Mouraouakkil, Radia Mounir, Mina Ait El Cadi, Jamal Lamsaouri, Yassir Bousliman, Rachid ElJaoudi
{"title":"[合成大麻素的毒理学]。","authors":"Youssef Mouraouakkil, Radia Mounir, Mina Ait El Cadi, Jamal Lamsaouri, Yassir Bousliman, Rachid ElJaoudi","doi":"10.1684/abc.2024.1888","DOIUrl":null,"url":null,"abstract":"<p><p>Synthetic cannabinoids (CS), or synthetic endocannabinoid receptor agonists, were initially synthesized for basic research into exocannabinoid signaling pathways, as well as in clinical research for their analgesic properties. The use of CS for recreational purposes is a recent phenomenon, but one that has grown very quickly in recent years, since these molecules now represent the main category of new synthetic products (NPS). This literature review aims to bring together current data regarding the use and effects caused by CS in humans. The relationship between the structure and activity of these CSs, the pharmacology and adverse effects of these CSs and finally the different methods of analyzing CSs. A better understanding of this phenomenon is essential to raise awareness among stakeholders in the health field.</p>","PeriodicalId":93870,"journal":{"name":"Annales de biologie clinique","volume":"82 2","pages":"151-173"},"PeriodicalIF":0.0000,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Toxicology of synthetic cannabinoids].\",\"authors\":\"Youssef Mouraouakkil, Radia Mounir, Mina Ait El Cadi, Jamal Lamsaouri, Yassir Bousliman, Rachid ElJaoudi\",\"doi\":\"10.1684/abc.2024.1888\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Synthetic cannabinoids (CS), or synthetic endocannabinoid receptor agonists, were initially synthesized for basic research into exocannabinoid signaling pathways, as well as in clinical research for their analgesic properties. The use of CS for recreational purposes is a recent phenomenon, but one that has grown very quickly in recent years, since these molecules now represent the main category of new synthetic products (NPS). This literature review aims to bring together current data regarding the use and effects caused by CS in humans. The relationship between the structure and activity of these CSs, the pharmacology and adverse effects of these CSs and finally the different methods of analyzing CSs. A better understanding of this phenomenon is essential to raise awareness among stakeholders in the health field.</p>\",\"PeriodicalId\":93870,\"journal\":{\"name\":\"Annales de biologie clinique\",\"volume\":\"82 2\",\"pages\":\"151-173\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-06-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annales de biologie clinique\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1684/abc.2024.1888\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annales de biologie clinique","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1684/abc.2024.1888","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

合成大麻素(CS)或合成内源性大麻素受体激动剂最初是为了对外源大麻素信号通路进行基础研究而合成的,在临床研究中也是为了获得其镇痛特性。将 CS 用于娱乐目的是最近才出现的现象,但近年来发展非常迅速,因为这些分子现已成为新合成产品(NPS)的主要类别。本文献综述旨在汇集有关 CS 的使用及其对人体影响的最新数据。这些 CS 的结构和活性之间的关系、这些 CS 的药理学和不良反应,以及分析 CS 的不同方法。更好地了解这一现象对于提高健康领域利益相关者的认识至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Toxicology of synthetic cannabinoids].

Synthetic cannabinoids (CS), or synthetic endocannabinoid receptor agonists, were initially synthesized for basic research into exocannabinoid signaling pathways, as well as in clinical research for their analgesic properties. The use of CS for recreational purposes is a recent phenomenon, but one that has grown very quickly in recent years, since these molecules now represent the main category of new synthetic products (NPS). This literature review aims to bring together current data regarding the use and effects caused by CS in humans. The relationship between the structure and activity of these CSs, the pharmacology and adverse effects of these CSs and finally the different methods of analyzing CSs. A better understanding of this phenomenon is essential to raise awareness among stakeholders in the health field.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信