小儿脑动静脉畸形的自然史和临床表现。

IF 1.4 4区 医学 Q4 CLINICAL NEUROLOGY
Adikarige Haritha Dulanka Silva, Greg James
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引用次数: 0

摘要

脑动静脉畸形(bAVM)是通过血管巢的异常动静脉分流,中间没有毛细血管床。脑动静脉畸形是导致儿童自发性颅内出血的最常见原因之一,一旦破裂可能会导致严重的发病率和死亡率。治疗策略包括显微外科切除术、血管内栓塞术、立体定向放射外科手术、多模式综合治疗,尤其是对高级别主动脉瘤采取保守治疗。参与治疗主动脉瘤的临床医生需要熟悉主动脉瘤的自然病史,包括破裂风险、增加破裂风险的危险因素以及了解主动脉瘤的临床表现。这篇特邀综述综述了动静脉畸形的自然史和临床表现,尤其关注儿童,为管理决策提供参考。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Natural history and clinical manifestation of Pediatric Brain Arteriovenous Malformations.

Brain arteriovenous malformations (bAVMs) are aberrant arteriovenous shunts through a vascular nidus with no intervening capillary beds. They are one of the commonest causes of spontaneous intracranial haemorrhage in children and may be associated with significant morbidity and mortality in cases of rupture. Treatment strategies include microsurgical resection, endovascular embolisation, stereotactic radiosurgery, multimodality treatment with a combination thereof, and particularly in high-grade bAVMs, conservative management. Clinicians involved in treating bAVMs need to have familiarity with the natural history pertaining to bAVMs in terms of risk of rupture, risk factors elevating rupture risk as well as understanding the clinical manifestations of bAVMs. This invited review serves to provide a synthesis on natural history and clinical presentation of bAVMs with particular focus in children to inform decision-making pertaining to management.

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来源期刊
CiteScore
2.90
自引率
6.20%
发文量
109
审稿时长
3-8 weeks
期刊介绍: The Journal of Korean Neurosurgical Society (J Korean Neurosurg Soc) is the official journal of the Korean Neurosurgical Society, and published bimonthly (1st day of January, March, May, July, September, and November). It launched in October 31, 1972 with Volume 1 and Number 1. J Korean Neurosurg Soc aims to allow neurosurgeons from around the world to enrich their knowledge of patient management, education, and clinical or experimental research, and hence their professionalism. This journal publishes Laboratory Investigations, Clinical Articles, Review Articles, Case Reports, Technical Notes, and Letters to the Editor. Our field of interest involves clinical neurosurgery (cerebrovascular disease, neuro-oncology, skull base neurosurgery, spine, pediatric neurosurgery, functional neurosurgery, epilepsy, neuro-trauma, and peripheral nerve disease) and laboratory work in neuroscience.
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