胰腺外分泌功能不全测试（PEI-TEST）在儿科患者中的适用性。

IF 1 4区医学 Q3 PEDIATRICS

Clinical Pediatrics Pub Date : 2025-01-01 Epub Date: 2024-05-09 DOI:10.1177/00099228241252212

Burcu Güven, Esra Özkaya, Serdar Karakullukçu, Mustafa Selçuk İmamoğlu, Murat Çakır

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引用次数: 0

摘要

在轻度病例中，很难诊断胰腺外分泌功能不全（PEI）。目前还没有诊断 PEI 的金标准方法。因此需要一种可靠的方法来初步诊断 PEI。PEI 测试适用于非特异性胃肠道症状的患者。对每位患者的血清淀粉酶、脂肪酶、血清胰蛋白酶原和粪便弹性蛋白酶 1（FE-1）进行了分析。根据 PEI 测试结果，42 名患者（47.7%）存在 PEI，46 名患者（52.3%）不存在 PEI。两组患者的年龄、性别、淀粉酶、脂肪酶、血清胰蛋白酶原和 FE-1 均无明显差异。当 FE-1 值为

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Applicability of the Pancreatic Exocrine Insufficiency Test (PEI-TEST) in Pediatric Patients.

In mild cases, it is difficult to diagnose pancreatic exocrine insufficiency (PEI). There is no gold standard method for the diagnosis of PEI. A reliable method is needed for preliminary diagnosis of PEI. The PEI-TEST was applied to the patients with nonspecific gastrointestinal complaints. Serum amylase, lipase, serum trypsinogen, and fecal elastase 1 (FE-1) were analyzed from each patient. According to the PEI-TEST, PEI was present in 42 (47.7%) and PEI was not present in 46 (52.3%) patients. No significant difference was observed between the 2 groups with regard to age, gender and amylase, lipase, serum trypsinogen, and FE-1. When an FE-1 value of <200 µg/dL was considered as indicating PEI, the sensitivity and specificity of the test were found to be 47.4% and 52.2%, respectively. Although it is promising that PEI-TEST is a validated test in our country and suitable for our society, it is not suitable for pediatric patients.

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来源期刊

Clinical Pediatrics 医学-小儿科

CiteScore

2.10

自引率

6.20%

发文量

189

审稿时长

3-8 weeks

期刊介绍： Clinical Pediatrics (CLP) a peer-reviewed monthly journal, is a must read for the busy pediatrician. CLP contains state-of-the-art, accurate, concise and down-to earth information on practical, everyday child care topics whether they are clinical, scientific, behavioral, educational, or ethical.