用于治疗结核病的配体添加异烟肼纳米颗粒系统的制备和体内外评估

IF 1.9 4区化学 Q4 CHEMISTRY, PHYSICAL

Journal of Dispersion Science and Technology Pub Date : 2024-05-05 DOI:10.1080/01932691.2024.2348511

Nimitt V. Chokshi, Vivek Bora, Shruti U. Rawal, Preksha Vinchhi, Saumitra Gajjar, Bhoomika M. Patel, Mayur M. Patel

引用次数: 0

摘要

异烟肼（INH）是治疗结核病（TB）的一线抗生素之一。尽管异烟肼具有很强的抗结核作用，但它对快速肝功能衰竭的敏感性却很高。

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Fabrication and in vitro–in vivo evaluation of ligand appended isoniazid loaded nanoparticulate systems for the treatment of tuberculosis

Isoniazid (INH) is amongst the first-line antibiotics that have been employed for the treatment of Tuberculosis (TB). Despite its potent anti-tubercular action, susceptibility to rapid hepatic firs...

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来源期刊

Journal of Dispersion Science and Technology 化学-物理化学

CiteScore

5.00

自引率

4.50%

发文量

140

审稿时长

1.1 months

期刊介绍： Journal of Dispersion Science and Technology is an international journal covering fundamental and applied aspects of dispersions, emulsions, vesicles, microemulsions, liquid crystals, particle suspensions and sol-gel processes. Fundamental areas that are covered include new surfactants, polymers and indigenous stabilizers; surfactant and polymer association as well as phase equilibria in systems water and oil; surfactant and polymer films, monolayers and interfacial films; adsorption and desorption onto solid surfaces; stability and destabilization of dispersions, emulsions and particle suspensions; collodal templates and sol-gel processing. Industrial applications cover chemicals, crude oils, food, pharmaceuticals, agriculture, nanotechnology, and soft condensed materials.