星状上区朗格汉斯细胞组织细胞增生症：甲状腺细胞学诊断

IF 3.5 2区医学 Q2 ENDOCRINOLOGY & METABOLISM

European Thyroid Journal Pub Date : 2024-05-01 DOI:10.1530/etj-24-0011

Maria Mavromati, Verdiana Caironi, Essia Saiji, Maria-Isabel Vargas, Shahan Momjian, Stephanie Andrade-Lopes, Capucine Gubert, Marco Stefano Demarchi, Ismini Mainta, François R. Jornayvaz, Kaveh Samii, Grégoire Stalder, Sophie Leboulleux

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引用次数: 0

摘要

朗格汉斯细胞组织细胞增生症（Langerhans cell histiocytosis，LCH）可能表现为鞍上区单灶疾病，伴有垂体功能减退、精氨酸加压素缺乏症（AVP-D）和体重增加等症状和体征。为了明确诊断和指导治疗决策，经颅活检是必要的，但会导致严重的发病率。我们描述了一名患有桥本甲状腺炎和单个下丘脑肿块的患者，尽管甲状腺影像学检查没有发现特异性结果，但通过甲状腺细针穿刺细胞学检查（FNAC），根据正电子发射断层扫描/计算机断层扫描（FDG-PET/-CT）中略微升高的[18F]-氟脱氧葡萄糖嗜性和随访期间的体积增大，对该患者进行了LCH诊断。

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Langerhans Cell Histiocytosis of the Suprasellar Region: Diagnosis on Thyroid Cytology

Langerhans cell histiocytosis (LCH) may present as unifocal disease of the suprasellar region, with symptoms and signs of hypopituitarism, arginine vasopressin deficiency (AVP-D) and weight gain. Transcranial biopsy is necessary, to define diagnosis and guide treatment decisions, but is associated with significant morbidity. We describe a patient with Hashimoto thyroiditis and a single hypothalamic mass in whom LCH diagnosis was done through thyroid fine-needle aspiration cytology (FNAC) performed despite nonspecific findings in thyroid imaging, on the basis of a slightly elevated [18F]-fluorodeoxyglucose avidity on positron emission tomography/-computed tomography (FDG-PET/-CT), and volume increase during follow-up.

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来源期刊

European Thyroid Journal Medicine-Endocrinology, Diabetes and Metabolism

CiteScore

6.70

自引率

2.10%

发文量

156

期刊介绍： The ''European Thyroid Journal'' publishes papers reporting original research in basic, translational and clinical thyroidology. Original contributions cover all aspects of the field, from molecular and cellular biology to immunology and biochemistry, from physiology to pathology, and from pediatric to adult thyroid diseases with a special focus on thyroid cancer. Readers also benefit from reviews by noted experts, which highlight especially active areas of current research. The journal will further publish formal guidelines in the field, produced and endorsed by the European Thyroid Association.