企业研发中的同步发现与发明:CRISPR 案例的启示

IF 3.4 3区 管理学 Q2 MANAGEMENT
Quentin Plantec, Pascal Le Masson, Benoît Weil
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引用次数: 0

摘要

一些公司投资于基础研究,但许多公司在开发新的内部科学知识并将其融入新发明时却举步维艰。虽然文献主张通过修订方法来更好地理解这一现象,但我们研究的是导致同步发现-发明(SDI)的过程。通过采用归纳过程,我们提出了一个模型,强调了 SDI 的机制。值得注意的是,我们揭示了在科学知识创造和发明产生的过程中,团队必须保持创造性探索的独立性,同时保持团队之间密集的原始知识交流。我们还证明,异常检测和同行验证机制是 SDI 的必要条件。我们以食品行业的一个案例研究来评估我们的模型:CRISPR-Cas9 是细菌的一种适应性防御免疫系统的发现以及该行业的相关创新。最后,我们将讨论我们的模型所提供的启示以及案例研究的意义。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Simultaneous Discovery–Invention in Corporate R&D: Lessons from the CRISPR Case
Some companies invest in fundamental research, but many struggle when developing novel in‐house scientific knowledge and integrating it into their new inventions. While the literature advocates revised approaches to better understand this phenomenon, we investigate the processes that lead to Simultaneous Discovery–Invention (SDI). By adopting an abductive process, we propose a model that highlights the mechanisms of SDI. Notably, we reveal that teams must preserve independence in creative exploration during scientific knowledge creation and invention generation while maintaining intensive original knowledge exchange among them. We also demonstrate that anomaly detection and peer validation mechanisms are mandatory for SDI. We evaluate our model with a case study in the food industry: the discovery that CRISPR–Cas9 is an adaptative defense immune system of bacteria and the associated innovations in this industry. Finally, we discuss the insights provided by our model and the implications of our case study.
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来源期刊
CiteScore
7.20
自引率
13.50%
发文量
52
期刊介绍: The European Management Review is an international journal dedicated to advancing the understanding of management in private and public sector organizations through empirical investigation and theoretical analysis. The European Management Review provides an international forum for dialogue between researchers, thereby improving the understanding of the nature of management in different settings and promoting the transfer of research results to management practice. Although one of the European Management Review"s aims is to foster the general advancement of management scholarship among European scholars and/or those academics interested in European management issues.
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