{"title":"托吡酯引起的眼部并发症:病例系列。","authors":"Sarita Lobo, Geover Joslen Lobo","doi":"10.22336/rjo.2024.14","DOIUrl":null,"url":null,"abstract":"<p><p>Several ocular adverse effects have been attributed to Topiramate, a sulfonamide derivative. It can cause problems in the eye such as choroidal effusion syndrome, acute angle closure glaucoma, myopic shift, visual field defects, and Myokymia. If not identified early, it can be vision-threatening. It is commonly used for migraine prophylaxis, partial onset, and generalized tonic-clonic seizures. It has also been prescribed for bipolar disorder and alcoholism. The risk of adverse reactions with this drug is 3%. The prognosis is favorable if it is discontinued early and prompt therapy is initiated.</p><p><strong>Objective: </strong>This article reported a case series of topiramate-induced ocular complications.</p><p><strong>Materials and methods: </strong>The patients presented with high intraocular pressure and blurred vision following a topiramate prescription for headache.</p><p><strong>Conclusion: </strong>Timely recognition and intervention can prevent potential visual loss in such cases.</p>","PeriodicalId":94355,"journal":{"name":"Romanian journal of ophthalmology","volume":"68 1","pages":"72-74"},"PeriodicalIF":0.0000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11007562/pdf/","citationCount":"0","resultStr":"{\"title\":\"Topiramate-induced ocular complications: case series.\",\"authors\":\"Sarita Lobo, Geover Joslen Lobo\",\"doi\":\"10.22336/rjo.2024.14\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Several ocular adverse effects have been attributed to Topiramate, a sulfonamide derivative. It can cause problems in the eye such as choroidal effusion syndrome, acute angle closure glaucoma, myopic shift, visual field defects, and Myokymia. If not identified early, it can be vision-threatening. It is commonly used for migraine prophylaxis, partial onset, and generalized tonic-clonic seizures. It has also been prescribed for bipolar disorder and alcoholism. The risk of adverse reactions with this drug is 3%. The prognosis is favorable if it is discontinued early and prompt therapy is initiated.</p><p><strong>Objective: </strong>This article reported a case series of topiramate-induced ocular complications.</p><p><strong>Materials and methods: </strong>The patients presented with high intraocular pressure and blurred vision following a topiramate prescription for headache.</p><p><strong>Conclusion: </strong>Timely recognition and intervention can prevent potential visual loss in such cases.</p>\",\"PeriodicalId\":94355,\"journal\":{\"name\":\"Romanian journal of ophthalmology\",\"volume\":\"68 1\",\"pages\":\"72-74\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11007562/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Romanian journal of ophthalmology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.22336/rjo.2024.14\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Romanian journal of ophthalmology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22336/rjo.2024.14","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Topiramate-induced ocular complications: case series.
Several ocular adverse effects have been attributed to Topiramate, a sulfonamide derivative. It can cause problems in the eye such as choroidal effusion syndrome, acute angle closure glaucoma, myopic shift, visual field defects, and Myokymia. If not identified early, it can be vision-threatening. It is commonly used for migraine prophylaxis, partial onset, and generalized tonic-clonic seizures. It has also been prescribed for bipolar disorder and alcoholism. The risk of adverse reactions with this drug is 3%. The prognosis is favorable if it is discontinued early and prompt therapy is initiated.
Objective: This article reported a case series of topiramate-induced ocular complications.
Materials and methods: The patients presented with high intraocular pressure and blurred vision following a topiramate prescription for headache.
Conclusion: Timely recognition and intervention can prevent potential visual loss in such cases.