C Pollak, J Verghese, A S Buchman, Y Jin, H M Blumen
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Models were adjusted for baseline age, gender, education, depressive symptoms, global cognition, and structural (e.g., social network, marital status), and functional social measures (e.g., social, cognitive, and physical activity, and social support).</p><p><strong>Participants: </strong>Loneliness and frailty data from 1,931 older adults without dementia at baseline from the Rush Memory and Aging Project were examined (mean age 79.6 ± 7.7 years, 74.9% female).</p><p><strong>Measurements: </strong>Baseline loneliness assessed by the de Jong Gierveld Loneliness Scale was the predictor of interest.</p><p><strong>Results: </strong>Frailty increased significantly over a mean follow-up period of 4.6 years. Effects of loneliness on frailty were modified by marital status. Loneliness predicted an additional accumulation of 0.37 and 0.34 deficits on the frailty index per year in married and widowed individuals respectively, compared to those who were not lonely (married: p=0.009, CI 0.09, 0.64; widowed: p=0.005, CI 0.1, 0.58). Loneliness did not predict frailty progression in unmarried individuals.</p><p><strong>Conclusions: </strong>Loneliness predicts frailty progression, highlighting the importance of social determinants on physical health in aging.</p>","PeriodicalId":51629,"journal":{"name":"Journal of Frailty & Aging","volume":null,"pages":null},"PeriodicalIF":3.3000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Loneliness Predicts Progression of Frailty in Married and Widowed, but Not Unmarried Community Dwelling Older Adults.\",\"authors\":\"C Pollak, J Verghese, A S Buchman, Y Jin, H M Blumen\",\"doi\":\"10.14283/jfa.2024.27\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Loneliness is highly prevalent among older adults and is associated with frailty. 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引用次数: 0
摘要
背景孤独在老年人中非常普遍，并且与虚弱有关。大多数研究都是孤立地考虑孤独感，而没有考虑社会关系的结构性和功能性措施，纵向研究也很少：本研究探讨了孤独与虚弱之间的纵向联系，并分析了结构性和功能性社会措施如何影响这些联系：线性混合效应模型检验了孤独感与以虚弱指数（0-100分）评估的虚弱程度之间的纵向联系。模型对基线年龄、性别、教育程度、抑郁症状、整体认知、结构性（如社交网络、婚姻状况）和功能性社会测量（如社交、认知、体育活动和社会支持）进行了调整：对拉什记忆与衰老项目（Rush Memory and Aging Project）中 1931 名基线无痴呆症的老年人（平均年龄为 79.6 ± 7.7 岁，74.9% 为女性）的孤独感和虚弱感数据进行了研究：基线孤独感由 de Jong Gierveld 孤独感量表评估：结果：在平均 4.6 年的随访期间，虚弱程度明显增加。孤独感对虚弱程度的影响受婚姻状况的影响。与不孤独的人相比，孤独感可预测已婚和丧偶的人每年在虚弱指数上分别多累积 0.37 和 0.34 的缺陷（已婚：P=0.009，CI 0.09，0.64；丧偶：P=0.005，CI 0.1，0.58）。孤独并不能预测未婚者的虚弱程度：结论：孤独感可预测衰弱的进展，这凸显了社会决定因素对老龄化过程中身体健康的重要性。
Loneliness Predicts Progression of Frailty in Married and Widowed, but Not Unmarried Community Dwelling Older Adults.
Background: Loneliness is highly prevalent among older adults and is associated with frailty. Most studies consider loneliness in isolation without consideration for structural and functional measures of social relationships - and longitudinal studies are scarce.
Objectives: This study examined longitudinal associations between loneliness and frailty and analyzed how structural and functional social measures influence these associations.
Design: Linear mixed effects models examined longitudinal associations between loneliness and frailty assessed with the frailty index (scale 0-100). Models were adjusted for baseline age, gender, education, depressive symptoms, global cognition, and structural (e.g., social network, marital status), and functional social measures (e.g., social, cognitive, and physical activity, and social support).
Participants: Loneliness and frailty data from 1,931 older adults without dementia at baseline from the Rush Memory and Aging Project were examined (mean age 79.6 ± 7.7 years, 74.9% female).
Measurements: Baseline loneliness assessed by the de Jong Gierveld Loneliness Scale was the predictor of interest.
Results: Frailty increased significantly over a mean follow-up period of 4.6 years. Effects of loneliness on frailty were modified by marital status. Loneliness predicted an additional accumulation of 0.37 and 0.34 deficits on the frailty index per year in married and widowed individuals respectively, compared to those who were not lonely (married: p=0.009, CI 0.09, 0.64; widowed: p=0.005, CI 0.1, 0.58). Loneliness did not predict frailty progression in unmarried individuals.
Conclusions: Loneliness predicts frailty progression, highlighting the importance of social determinants on physical health in aging.
期刊介绍：
The Journal of Frailty & Aging is a peer-reviewed international journal aimed at presenting articles that are related to research in the area of aging and age-related (sub)clinical conditions. In particular, the journal publishes high-quality papers describing and discussing social, biological, and clinical features underlying the onset and development of frailty in older persons. The Journal of Frailty & Aging is composed by five different sections: - Biology of frailty and aging In this section, the journal presents reports from preclinical studies and experiences focused at identifying, describing, and understanding the subclinical pathophysiological mechanisms at the basis of frailty and aging. - Physical frailty and age-related body composition modifications Studies exploring the physical and functional components of frailty are contained in this section. Moreover, since body composition plays a major role in determining physical frailty and, at the same time, represents the most evident feature of the aging process, special attention is given to studies focused on sarcopenia and obesity at older age. - Neurosciences of frailty and aging The section presents results from studies exploring the cognitive and neurological aspects of frailty and age-related conditions. In particular, papers on neurodegenerative conditions of advanced age are welcomed. - Frailty and aging in clinical practice and public health This journal’s section is devoted at presenting studies on clinical issues of frailty and age-related conditions. This multidisciplinary section particularly welcomes reports from clinicians coming from different backgrounds and specialties dealing with the heterogeneous clinical manifestations of advanced age. Moreover, this part of the journal also contains reports on frailty- and age-related social and public health issues. - Clinical trials and therapeutics This final section contains all the manuscripts presenting data on (pharmacological and non-pharmacological) interventions aimed at preventing, delaying, or treating frailty and age-related conditions.The Journal of Frailty & Aging is a quarterly publication of original papers, review articles, case reports, controversies, letters to the Editor, and book reviews. Manuscripts will be evaluated by the editorial staff and, if suitable, by expert reviewers assigned by the editors. The journal particularly welcomes papers by researchers from different backgrounds and specialities who may want to share their views and experiences on the common themes of frailty and aging.The abstracting and indexing of the Journal of Frailty & Aging is covered by MEDLINE (approval by the National Library of Medicine in February 2016).
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