对同时感染 COVID-19 和肺曲霉菌病的病例进行分析。

IF 1.5 4区医学 Q4 MICROBIOLOGY

New Microbiologica Pub Date : 2024-05-01

Hui Zheng Hu, Li Bo Wu, Qian Liu, Bin Yan Wu, Yu Wang, Rui Ying Wang

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引用次数: 0

摘要

本研究旨在探讨COVID-19相关肺曲霉菌病（CAPA）的风险因素和诊断措施。本研究纳入了2022年12月1日至2023年1月31日期间的201例COVID-19患者，其中7例（3.5%）被确诊为CAPA。主要风险因素为年龄、MV、入住ICU和COPD，COVID-19患者存在ARDS和低蛋白血症等合并症，更易感染曲霉菌。除下呼吸道标本培养外，1,3-β-D-葡聚糖抗原检测可作为非粒细胞减少症患者早期诊断 CAPA 的重要筛查指标。

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Analysis of cases with co-infection of COVID-19 and pulmonary aspergillosis.

The objective of this study was to investigate the risk factors and diagnosis measure of COVID-19-associated pulmonary aspergillosis (CAPA). This study included 201 COVID-19 patients from December 1, 2022, to January 31, 2023; 7 (3.5%) were diagnosed with CAPA. The main risk factors were age, MV, ICU admission and COPD, and the presence of comorbidities such as ARDS and hypoproteinemia in COVID-19 patients, more susceptible to Aspergillus infection. In addition to specimen culture in the lower respiratory tract, the 1,3-β-D-glucan antigen test can serve as an important screening indicator for early CAPA diagnosis in non-granulocytopenia patients.

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来源期刊

New Microbiologica 生物-微生物学

CiteScore

2.20

自引率

5.60%

发文量

审稿时长

6-12 weeks

期刊介绍： The publication, diffusion and furtherance of research and study on all aspects of basic and clinical Microbiology and related fields are the chief aims of the journal.