额颞叶痴呆症综述:对语言、言语和行为的影响。

Q3 Medicine
Dementia e Neuropsychologia Pub Date : 2024-04-22 eCollection Date: 2024-01-01 DOI:10.1590/1980-5764-DN-2023-0072
Sha Abbas Mollah, Aditya Nayak, Swapna Barhai, Uddip Maity
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引用次数: 0

摘要

额颞叶痴呆症(FTD)是一种进行性神经退行性疾病,表现为大脑额叶和颞叶的选择性退化。本综述探讨了 FTD 对语言、言语和行为的影响。早期症状包括找词困难、言语输出减少和理解障碍,通常会导致失语。该研究讨论了在 FTD 患者身上观察到的深刻行为变化,包括冷漠、抑制、强迫行为和移情能力丧失,以及早期准确诊断的重要性和面临的挑战。我们甚至回顾了靶向疗法的潜力,以及多学科护理在管理 FTD 的语言、言语和行为方面所起的重要作用。通过对客观数据和相关综合研究的审查,本研究为了解 FTD 对语言、言语和行为的深刻影响提供了宝贵的见解,有助于改善临床管理,并为这一毁灭性疾病提供潜在的治疗策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A comprehensive review on frontotemporal dementia: its impact on language, speech and behavior.

Frontotemporal dementia (FTD) is a progressive neurodegenerative disorder defined by the selective deterioration of the frontal and temporal lobes of the brain. This comprehensive review explored the effect of FTD on language, speech, and behavior. Early symptoms include difficulty in word finding, reduced speech output, and comprehension deficits, often leading to aphasia. The study discussed the profound behavioral changes observed in FTD patients, including apathy, disinhibition, compulsive behaviors, and loss of empathy, the importance of an accurate and early diagnosis, and its challenges. We even reviewed the potential for targeted therapies and the essential role of multidisciplinary care in managing the language, speech, and behavioral aspects of FTD. By examining objective data and comprehensive research on the subject, this study offers valuable insights into FTD's profound effects on language, speech, and behavior, assisting in improved clinical management and potential therapeutic strategies for this devastating condition.

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来源期刊
Dementia e Neuropsychologia
Dementia e Neuropsychologia Medicine-Geriatrics and Gerontology
CiteScore
2.20
自引率
0.00%
发文量
58
审稿时长
8 weeks
期刊介绍: Dementia top Neuropsychologia the official scientific journal of the Cognitive Neurology and Ageing Department of the Brazilian Academy of Neurology and of the Brazilian Association of Geriatric Neuropsychiatry, is published by the "Associação Neurologia Cognitiva e do Comportamento", a nonprofit Brazilian association. Regularly published on March, June, September, and December since 2007.
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