儿童时期斜视手术时间与心理健康的关系:一项回顾性队列研究。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Ian Hidinger BS , Lan Kong MS, PhD , Amanda Ely MD
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引用次数: 0

摘要

目的:在儿童期接受斜视手术的早期斜视诊断儿童中,调查精神病诊断的发生率与斜视手术时间的关系:我们利用2003-2023年的TriNetX网络数据,对≤5岁时诊断为斜视并在18岁前接受斜视手术的患者进行了一项回顾性队列研究。队列 1 包括在≤6 岁时接受初次斜视手术的患者;队列 2 包括在≥7 岁时接受初次手术治疗的患者。比较了不同组群患者在 7 至 18 岁期间的心理健康诊断发生率:在队列 1 中,688 名患者中有 59 人(8.6%)被诊断患有至少一种精神疾病,而在队列 2 中,693 名患者中有 123 人(17.7%)被诊断患有至少一种精神疾病(风险比 [RR] = 2.07;95% CI,1.546 至 2.77;P <0.0001)。性别分析显示,与队列 1 相比,队列 2 中只有男性的精神健康诊断率有显著的统计学增长(RR = 1.82;95% CI,1.284 至 2.577;P = 0.006)。与队列 1 相比,队列 2 中特定精神病诊断的风险增加:焦虑症(RR = 2.19;95% CI,1.225-3.922;P = 0.0065)、注意力缺陷/多动症(RR = 2.18; 95% CI, 1.499-3.175; P < 0.0001)、行为障碍(RR = 2.81; 95% CI, 1.425-5.556; P = 0.0018)和适应障碍(RR = 2.07; 955% CI, 1.103-3.876; P = 0.0204)。各组间的抑郁障碍在统计学上无显著差异(RR = 1.00;95% CI,0.419-2.392;P = 0.9974):结论:与早期接受斜视手术的儿童相比,那些在≤5岁时被诊断为早期斜视后较晚才接受手术的儿童可能更容易在童年时期出现心理健康障碍,但目前还不清楚这些障碍是延迟手术的结果,还是选择手术而非继续保守治疗的驱动因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Associations of strabismus surgery timing in childhood with mental health: a retrospective cohort study

Purpose

To investigate the incidence of psychiatric diagnoses in relation to strabismus surgery timing among children with an early strabismus diagnosis who underwent surgery in childhood.

Methods

We conducted a retrospective cohort study using TriNetX network data from 2003-2023 on patients diagnosed with strabismus at ≤5 years of age and having strabismus surgery before 18 years of age. Cohort 1 comprised patients who underwent initial strabismus surgery at ≤6 years of age; cohort 2, patients with initial surgical intervention at ≥7 years of age. Incidence of mental health diagnoses from 7 until 18 years of age were compared between cohorts.

Results

In cohort 1, 59 of 688 patients (8.6%) of patients were diagnosed with at least 1 mental health disorder versus 123 of 693 patients (17.7%) in cohort 2 (risk ratio [RR] = 2.07; 95% CI, 1.546 to 2.77; P < 0.0001). Gender analysis showed that only males had a statistically significant increased rate of mental health diagnoses in cohort 2 versus cohort 1 (RR = 1.82; 95% CI, 1.284 to 2.577; P = 0.006). An increased risk for specific psychiatric diagnoses was found in cohort 2 versus cohort 1; anxiety disorders (RR = 2.19; 95% CI, 1.225-3.922; P = 0.0065), attention-deficit / hyperactivity disorder (RR = 2.18; 95% CI, 1.499-3.175; P < 0.0001), conduct disorders (RR = 2.81; 95% CI, 1.425-5.556; P = 0.0018), and adjustment disorders (RR = 2.07; 955% CI, 1.103-3.876; P = 0.0204). Depressive disorders showed no statistically significant difference between cohorts (RR = 1.00; 95% CI, 0.419-2.392; P = 0.9974).

Conclusions

Compared with children having early strabismus surgery, those having surgery at a later age after an early strabismus diagnosis at ≤5 years of age may be more likely to experience a mental health disorder during childhood, although it is unclear whether such disorders are a result of delayed surgery or a driver of the decision to opt for surgery rather than continued conservative management.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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